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TissueDB/Materials/Ink or Dye

From Appropedia
Four bottles of liquid food colouring — blue, red, green and yellow — with the coloured liquid visible through the glass
Four bottles of liquid food colouring — blue, red, green and yellow.
License: CC-BY-2.0 by Larry Jacobsen

Ink or dye is a colourant — liquid, gel, powder or paint — used in medical simulation to give a fluid or a model surface a realistic colour; in TissueDB builds, most often red to mimic blood. A dye is mixed into water or saline to make simulated blood, or added to a fluid circuit so that a leak becomes visible. A paint is brushed onto a model to colour anatomy, mark a landmark, or finish a surface. The many named colours, forms and brands are grouped as one material class because the colour is a detail of the same colourant, not a different material.

Tissues

Tissue Visual Tactile Simulator Notes
Blood Peripheral Intravenous Catheterization Trainer, Hemorrhage Control Simulator (Malik), Synthetic Tourniquet Training Model (Souza Lima), Suction-Assisted Laryngoscopy and Airway Decontamination Simulator (Kumar), Cricothyrotomy Simulator (Calvo), Cricothyrotomy Simulator (Kei), Intra-abdominal Bleeding Simulator (Fernandes), Massive Hemoptysis Simulator (New), Superficial Temporal Artery-Middle Cerebral Artery Bypass Trainer The Peripheral IV trainer lists optional red food colouring.[1] Malik uses red food colouring with saline or other IV fluid.[2] Calvo and Kei use red-dyed saline.[3][4] Kumar uses red food colouring in water.[5] Souza Lima uses red school paint diluted with water.[6] New adds blue food colouring and corn starch to the red mixture.[7] Fernandes lists five units of food colouring.[8] The STA–MCA trainer uses Rifocin-coloured water.[9]
(Structural — leak-indicator dye, not tissue simulant) Grapefruit dACA Bypass Simulator Red food colouring makes leaks visible in the water circuit.[10]
(Structural — surface finish on a paper-mache model, not tissue simulant) Bronchoscopy Anatomical Trainer (Di Domenico) Water-based enamel finish for the paper-mache airway model.[11]
(Structural — landmark marking and vessel colour-coding, not tissue simulant) Laparoscopic Inguinal Hernia Repair Simulator (Hanssen) White paint identifies the Cooper’s-ligament landmark; blue and red paint distinguish the iliac-vessel stand-ins.[12]
(Structural — anatomical colouring of a 3D-printed model, not tissue simulant) Laparoscopic Inguinal Hernioplasty TAPP 3D Simulator (Pires de Melo Filho) Gouache ink in anatomy-book colours for the printed male pelvis.[13]
Application role not specified in source Abdominal Wall Defect Simulator (Medeiros) Fake blood makeup; 20 mL is listed for the two-model build. The exact application site and amount per model are unspecified. Reviewers noted possible confusion with bowel damage; removal was suggested for a future version.[14]
(Structural — colouring cast plastisol sheets, not tissue simulant) Emergency Department Thoracotomy Simulator (Misra) Colourant for plastisol skin and fat sheets, listed as two 4 oz packs. The build yields ten pairs of sheets; no colourant mixing ratio is given.[15]
(Structural — pigmenting cast silicone, not tissue simulant) Injection Laryngoplasty Simulator (Lee), Laparoscopic Cholecystectomy Simulator (Casas-Murillo) Lee uses Silc-Pig PMS 7421C and 488C in Ecoflex 00-20 for a pink endolarynx.[16] Casas-Murillo uses colourant in P53 silicone for the gallbladder and bile ducts; the figure caption shows green dye, without a brand or colour code.[17]
(Structural — colouring the cast gelatin block, not tissue simulant) Patent Ductus Arteriosus Ligation Simulator Powdered red pigment colours the gelatin model.[18]
(Structural — opacifying a gelatin phantom for blinded training, not tissue simulant) Pediatric Forearm Fracture Simulator Food colouring makes the gelatin phantom opaque for blinded training; the unblinded version stays transparent.[19]
(Structural — colourant listed among assembly materials) Pediatric Inguinal Hernia Repair Simulator (Heo) The source lists Rit Dye in yellow, tangerine and cherry red among the purchased assembly materials; it does not assign these dyes to particular components or give a mixing amount.[20]
Vomit Suction-Assisted Laryngoscopy and Airway Decontamination Simulator (Kumar) Green food colouring in water represents vomit.[5]
Vessel-wall stain (methylene blue) Superficial Temporal Artery-Middle Cerebral Artery Bypass Trainer Methylene blue highlights the vessel wall at the vessel ends.[9]
(Structural — colouring the bowel stand-in, not tissue simulant) Trocar Placement Simulator Red lipstick colours the balloon used as the bowel stand-in.[21]
(Structural — colouring gelatin tissue layers, not tissue simulant) Z-Plasty Simulator Red food colouring for muscle, yellow for fat, and pink/white/yellow for skin; amounts vary with the desired skin tone. The connective-tissue paste contains no colouring.[22]
(Structural — drawing muscle-fibre striations on the batting muscle layers, not tissue simulant) Open Appendectomy Simulator (Matthews) Red marker distinguishes the perpendicular fibre directions of the two cotton-batting muscle layers. Reviewer feedback requested more colour and larger stripes.[23]








References

  1. ↑ Stephanie McKee. "Caboodle Noodle 2.0." NLN SIRC HomeGrown Solutions, Solution 394. NLN source.
  2. ↑ Malik OAA, Chhapra R. An Inexpensive model to teach hemorrhage control in resource limited settings. Pak J Med Sci. 2021;37(3):916–918. DOI: 10.12669/pjms.37.3.3517. PMID: 34104189.
  3. ↑ Calvo A, Ibañez Esteve C, Varela V, Gomez-Lopez L, Perdomo JM, Berge R, Gomar Sancho C. Design, application and evaluation of a cricothyrotomy model for a multidisciplinary simulation. An observational single centre study. Educación Médica 2021;22:305–310. DOI: 10.1016/j.edumed.2020.12.003.
  4. ↑ Kei J, Mebust DP, Duggan LV. The REAL CRIC Trainer: Instructions for Building an Inexpensive, Realistic Cricothyrotomy Simulator with Skin and Tissue, Bleeding, and Flash of Air. Journal of Emergency Medicine 2019;56(4):426–430. DOI: 10.1016/j.jemermed.2018.12.023. PMID: 30685221.
  5. ↑ 5.0 5.1 Kumar R, Kumar R. An Indigenous Suction-assisted Laryngoscopy and Airway Decontamination Simulation System. Indian Journal of Critical Care Medicine 2024;28(7):702–705. DOI: 10.5005/jp-journals-10071-24760. PMID: 38994267. PMC: PMC11234124. License: CC BY-NC 4.0.
  6. ↑ Souza Lima D, Almeida YADS, Cid DMC, Cardoso LC, Braga CS, Regis FGL. Low-cost synthetic tourniquet training model. Rev Col Bras Cir. 2019;46(6):e20192324. DOI 10.1590/0100-6991e-20192324. PMID 31967244.
  7. ↑ New ML, Amass T, Neumeier A, Jacobson NM, Huie TJ. Creation and validation of a massive hemoptysis simulator. Chest 2024;165(3):636–644. DOI: 10.1016/j.chest.2023.10.014. PMID 37852436.
  8. ↑ Fernandes CO, Rodrigues LR, Silva do Amaral MLBS, de Morais Rodrigues SJ, Marton-Filho MA. Low-cost simulator for intra-abdominal bleeding. Rev Col Bras Cir 2023;50:e20233512. DOI: 10.1590/0100-6991e-20233512-en. PMID: 37971114. PMC: PMC10618030.
  9. ↑ 9.0 9.1 Akdag BA, Akdag B, Ikizoglu E, Husemoglu B, Kizmazoglu C, Aydin HE, Ozer E. "A Novel Training Model for Superficial Temporal Artery- Middle Cerebral Artery Anastomosis Using Microsurgical Techniques." World Neurosurgery. 2024;190:e665–e674. DOI 10.1016/j.wneu.2024.07.200. PMID 39098505.
  10. ↑ Cikla U, Rowley P, Jennings Simoes EL, Ozaydin B, Goodman SL, Avci E, Baskaya MK, Patel NJ. Grapefruit Training Model for Distal Anterior Cerebral Artery Side-to-Side Bypass. World Neurosurgery 2020;138:39–51. DOI 10.1016/j.wneu.2020.02.107. PMID 32109640.
  11. ↑ Di Domenico S, Simonassi C, Chessa L. Inexpensive anatomical trainer for bronchoscopy. Interactive CardioVascular and Thoracic Surgery 2007;6(4):567–569. DOI 10.1510/icvts.2007.153601. PMID 17669940.
  12. ↑ Hanssen A, Hanssen DA, Hanssen RA, Plotnikov S, Haddad J, Daes JE. Implementation and Validation of a Novel and Inexpensive Training Model for Laparoscopic Inguinal Hernia Repair. J Abdom Wall Surg 2022;1:10305. DOI 10.3389/jaws.2022.10305. CC BY 4.0.
  13. ↑ Pires de Melo Filho L, Mano Almeida A, Marçal de Barros Filho E, de Oliveira Borges GC. Simulated training model in a low cost for laparoscopic inguinal hernioplasty. Acta Cir Bras. 2021;36(1):e360108. doi:10.1590/ACB360108. CC BY 4.0.
  14. ↑ Medeiros GA, Gualberto IJN, da Silva CHND, Diniz AMB, de Santana JBF, Volpe FP, Gadde R, Mazzo A, de Oliveira RC, Sbragia L. Development of a low-cost congenital abdominal wall defect simulator (wall-go) for undergraduate medical education: a validation study. BMC Medical Education. 2023;23(1):966. Open access (CC BY 4.0). DOI: 10.1186/s12909-023-04929-3. PMID 38102605.
  15. ↑ Misra A, Chapman A, Watson WD, Bach JA, Bonta MJ, Elliott JO, Dominguez EP (2024). "Use of Low-Cost Task Trainer for Emergency Department Thoracotomy Training in General Surgery Residency Program." Journal of Surgical Education 81(1):134–144. DOI: 10.1016/j.jsurg.2023.09.009. PMID: 37926660. © 2023 Association of Program Directors in Surgery, published by Elsevier Inc. All rights reserved.
  16. ↑ Lee M, Ang C, Andreadis K, Shin J, Rameau A. An open-source three-dimensionally printed laryngeal model for injection laryngoplasty training. Laryngoscope 2021;131(3):E890–E895. DOI: 10.1002/lary.28952. PMID: 32750164.
  17. ↑ Casas-Murillo C, Zuñiga-Ruiz A, Lopez-Barron RE, Sanchez-Uresti A, Gogeascoechea-Hernandez A, Muñoz-Maldonado GE, Salinas-Chapa M, Elizondo-Riojas G, Negreros-Osuna AA. 3D-printed anatomical models of the cystic duct and its variants, a low-cost solution for an in-house built simulator for laparoscopic surgery training. Surgical and Radiologic Anatomy 2021;43(4):537–544. DOI 10.1007/s00276-020-02631-3. PMID 33386458.
  18. ↑ Cardiac Surgical Skills Training Module, SELF-Training team / Global Surgical Training Challenge, Appropedia, 2021. Build and operation: Phase 2 (Simulator Setup), Phase 3 (Skills Practice) and Phase 4 (Self-Assessment).
  19. ↑ Pediatric Distal Forearm Fractures/Pediatric Forearm Simulators, Appropedia.
  20. ↑ Heo K, Greaney E, Haehl J, Stunden C, Lindner A, Malik PRA, Rosenbaum DG, Muensterer O, Zakani S, Jacob J, Joharifard S. Iterative Design and Manufacturing of a 3D-Printed Pediatric Open and Laparoscopic Integrated Simulator for Hernia Repair (POLISHeR). Journal of Pediatric Surgery 2025;60:162232. DOI 10.1016/j.jpedsurg.2025.162232 PMID 40011165. CC BY-NC 4.0.
  21. ↑ ALL-SAFE Consortium. ALL-SAFE Trocar Placement Simulation Build Instructions. Pan-African Academy of Christian Surgeons, University of Michigan, Southern Illinois University, Soddo Christian Hospital, AIC Kijabe Hospital, Mbingo Baptist Hospital. Available at: PDF.
  22. ↑ AmoSmile Physical Simulator. AmoSmile team, Appropedia.
  23. ↑ Matthews J, Bhatia MB, Thomas C, Okoth P, Martinez CR, Levy JS, Stefanidis D, Hunter-Squires JL, Saruni SI (2022). "AMPATH surgical app: Low-cost simulator for the open appendectomy." Surgery 172(6):1656–1664. DOI: 10.1016/j.surg.2022.07.023. PMID: 36123174. © 2022 Elsevier Inc.


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