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This module provides data-driven, gender-specific, easy to print, labor-saving, environmentally friendly, hygienic, and cruelty-free bone simulation models that are not made with natural rubber latex, are designed with safety features to protect users, and can be locally reproduced to provide the highest fidelity, standardized orthopedic surgical simulation training at the lowest cost.

Innovative Design[edit | edit source]

This module provides data-driven, gender-specific, easy to print, labor-saving, environmentally friendly, hygienic, and cruelty-free bone simulation models that are not made with natural rubber latex, are designed with safety features to protect users, and can be locally reproduced to provide the highest fidelity, standardized orthopedic surgical simulation training at the lowest cost.

Safety By Design[edit | edit source]

Our team has prioritized safety in the design of our simulators.

All of the module's 3D printed bone models have a vise attachment to allow the user to secure the model inside a standard vise clamp to maximize safety during simulation training. Although using a vise clamp is more costly, it is standard training practice for bone models to be secured inside a vise clamp to maximize safety during bicortical drilling and fracture fixation simulation training.[1][2][3][4] Based on our clinical experience and user testing, we do not recommend having an assistant hold a bone model during drilling training because this exposes the assistant to potential injury. There is always a risk that the drill bit may slip when drilling through the bone simulation model during training.[5]

This training module instructs all learners to wear proper protective equipment (protective eyewear and gloves) during the simulation skills training in accordance with "The ten best practices for healthcare simulation safety" as listed on the Foundation for Healthcare Simulation Safety website.[6]

High Fidelity[edit | edit source]

To maximize learning efficiency and minimize simulator overall costs and assembly time, we provide high fidelity, standardized bone simulation models for basic and advanced simulation training instead of having the learner progress through a range of homemade (DIY) simulators of varying and increasing fidelity.

These 3D printed models accurately simulate bone length and diameter, external contour and cross-sectional shape, bicortical anatomy, cortical hardness, cancellous bone porosity, and microstructure, and far cortex thickness for both genders at drilling sites for humeral shaft fractures.[7][8][9][10][11][12][13][14][15][16][17][18][19][20][21][22][23]

The maximum length of the humerus (mean ± standard deviation) ranges from 305.42 + 1.4 mm to 330.67 + 3.5 mm across different populations.[9][10][11] Cortical thickness varies depending on gender, age, and regions in the humerus. A 2015 review paper found that humeral shaft fractures occur in young male adults in 55–63% of cases.[24] We reviewed a 1963 study on 1,214 subjects to extrapolate the mean cortical thickness values of the distal end of the humeral shaft for Canadian female and male adults ages 21-45 years was ~4.5 mm (normal range: 3.5-6.0 mm) and 5.5 mm (normal range: 3.5-7.5 mm), respectively.[21] We reviewed a 1980 study on Bantu women (all of whom belonged to the Xhosa tribe) ages 20-40 to calculate that the average cortical thickness value for the lower right humeral shaft is 4.47 mm (SD + 0.41 mm).[22] We also reviewed a 1970 study on Caucasian women aged 20-39 years and estimated the normal range of cortical thickness values for the left humeral distal shaft is 3.75-5.0 mm.[23] The 3D printed bone models are designed to accurately simulate far cortex thickness values for young (< 45 years) adult males and females at humeral diaphyseal drilling sites for modular external fixation.[21][22][23][24]

During bicortical drilling skills training, the learner adjusts the applied drilling force to minimize plunge depth.[25] Drilling forces are influenced by cortical thickness, bone site, patient age, and bone mineral density.[26] To minimize the risk of teaching anti-skills (excessive or inadequate drilling forces), the high fidelity 3D printed bone models are made of plastic with similar hardness to human cortical bone and are designed to accurately simulate the age, gender, and bone site-specific cortical thickness values and cancellous bone porosity for the target patient population.[14][15][21][22][23][24][27]

A simulator without augmented (extrinsic) feedback is a higher fidelity simulator than a simulator with augmented feedback because this more accurately reflects real clinical scenarios. Thus, we did not include the augmented feedback feature for plunge detection for the Humeral Shaft Transverse Fracture Simulator to provide higher fidelity modular external fixation skills training to learners.

Easy to Manufacture[edit | edit source]

3D printing technology empowers local, labor-saving, and automated reproduction of high fidelity bone simulation models to permit standardized, high quality, self-assessed simulation training in LMICs. Using our high fidelity 3D printed bone models substantially simplifies the simulator build, minimizes the simulator assembly time, and accelerates the learning process for greater convenience for the learner.

High fidelity 3D printed surgical simulation models are typically made on expensive ($300,000 USD), closed system printers that use costly, proprietary filaments ($302.50 - $432.26/kg USD) and software and require a team of highly trained professionals to operate and maintain.[28][29] These high priced 3D printed anatomic models generally require time-consuming, laborious, and multi-step digital file preparation and significant post-processing of the 3D printed model before use by the practitioner.[28][29][30][31]

All of the module's 3D printed bone simulation models are open source and can be locally reproduced on open-source, open filament, user friendly, single extruder desktop 3D printers that print polylactic acid (PLA), a low-cost and easy to print plastic.[32][33][34][35][36][37][38]

To minimize material, equipment and labor costs during production, all of the module's 3D printed bone models are designed to:

  1. print without support material, rafts or brims
  2. require no cleaning, sanding, gluing, priming, painting, dipping, coating, smoothing, polishing, or any post-processing
  3. not require any non-3D printed parts, and
  4. be ready for use right out of the 3D printer.[39]

The Humeral Shaft Transverse Fracture Simulator is easy and quick to assemble and do not require any tools, specialized equipment, technical expertise, or time-consuming preparation to build, install, operate and maintain these simulators within the intended place of use.

Lower Cost[edit | edit source]

The 3D Printed Adult Humeral Bone Models can be locally reproduced to provide the highest fidelity simulators at the lowest cost for orthopedic surgical simulation training. The costs of the 3D Printed Adult Humeral Bone Models will vary depending on the region's 3D printing organizations, and locally available brands of filament.

In Canada, a 1.0 kg roll of white PLA costs $17.95 CAD which is equal to about 1.4¢ USD per gram.[40][41] The Humeral Shaft Transverse Fracture Simulator (3D Printed Adult Male Humeral Bone Models #1 and #2) weighs 281 grams and the total filament cost in Canada is $3.93 USD.

In Nigeria, one 750 gram roll of Ultimaker White PLA filament (Shore Hardness 83D) costs €33 Euros which is equal to about 5¢ USD per gram.[42][43] In 2022, the 3D Printed Adult Male Humeral Bone Models #1 and #2 produced by a local 3D printing business in Nigeria at 100% scale is $11.65 and $11.32 USD (not including local taxes or shipping costs).[44] The estimated filament weight and printing times for the 3D Printed Adult Male Humeral Bone Models #1 and #2 at 100% scale are 143 grams and 138 grams and 6 hours and 15 minutes, and 6 hours and 5 minutes, respectively.

The Humeral Shaft Transverse Fracture Simulator is easy and quick to assemble and does not require any tools, specialized equipment, technical expertise, or time-consuming preparation to build, install, operate and maintain this simulator within the intended place of use. The benefits of 3D printing the Humeral Shaft Transverse Fracture Simulator (3D Printed Adult Humeral Bone Models #1 and #2) locally in Nigeria are that the purchase cost is over 10 times cheaper and the production time is over 163 times faster than purchasing a comparable artificial bone product that is imported from abroad, and the purchase cost is over 3 times cheaper than acquiring a human cadaveric humerus prepared by a local university anatomy lab.[44][45][46] By purchasing locally made 3D printed bone models for modular external fixation skills training, the learner also supports the local economy while saving on customs dues, processing fees, and international shipping costs that would be incurred when using artificial bone products that are not made locally.

2022 Comparison of Humeral Shaft Transverse Fracture Simulator Locally Made in Nigeria to Human Cadaveric Bone and a Commercially Available Artificial Bone Product
Humeral Shaft Transverse Fracture Simulator

(3D Printed Adult Male Humeral Bone Models #1 and #2)

Human Cadaveric Humerus

(Prepared by an University Anatomy Lab in Nigeria)[46]

Sawbones Humerus, 4th Gen., Composite, 10 PCF Solid Foam Core, Large, Left

(SKU:3404-4)[47]

Bone Simulator Dimensions Humerus with an overall length of 33 cm.[9][10][11] Varies.[9][10][11] Humerus with an overall length of 36.5 cm.
Bone Simulator Features 3D printed anatomic bone models reproduce bicortical anatomy, cortical thickness, and cancellous bone to provide acoustic fidelity when drilling through the bone simulator.
  • Human cadaveric humeral bone specimen prepared by an anatomy lab.
  • Age of donor may not be known.
  • Requires wet storage (which incurs additional fees)
Humerus contains "short fiber filled epoxy as the simulated cortical bone material," "a 10 PCF density cancellous foam core, and a 9 mm diameter canal."[47]
Tactile Fidelity Made of biorenewable plastic with a hardness level that is very similar to human cortical bone to allow learners to develop the skills to prevent plunging through the far cortex. Human cadaveric humeral bone Sawbones Composite Bones are the only Sawbones products that "mimic the [biomechanical] properties of human bones," and "are used as alternative testing media to human cadaver bone."[47][48]
Visual Fidelity Yes. White colour Yes. White colour No. Gray/green colour[47]
Fracture Simulation Simulates a transverse mid-shaft fracture of the humerus for modular external fixation training. Requires additional preparation to simulate a fracture. Requires additional preparation by user to simulate a fracture.
Fracture Encapsulation Encapsulates transverse fracture with cellophane. No. This would incur additional preparation and storage fees. Does not encapsulate or re-attach fracture.
Vise Attachment Contains a vise attachment to safely secure the model inside a standard vise clamp or to the side of a table or wood board. Does not contain a vise attachment which mandates the use of specialized vise clamps that cost up to $214 USD to properly secure the model to a table for safe simulation training for learners. Does not contain a vise attachment which mandates the use of specialized vise clamps that cost up to $214 USD to properly secure the model to a table for safe simulation training for learners.
Production Time 12 hours 20 minutes (when Adult Male Humeral Bone Models #1 and #2 are printed consecutively). Depends on local availability of cadaver specimens which is difficult to predict. Ready to ship in 84 days or more.[47]
Purchase Cost (not including local taxes or shipping costs) $22.97 USD[44] $75.00 USD[46] $229.75[47]

Noteː A product comparison was not made with the:

  • Sawbones Humerus, Solid Foam, Right, ($15.00 USD) because this model simulates the intramedullary canal but not cancellous bone, and the foam material does not simulate the hardness of cortical bone and thus, could foster anti-skills, and
  • Sawbones Humerus with Oblique Fracture, Foam Cortical ($41.50 USD) because this model's rigid foam shell cuts and drills easier than the plastic cortical shell models and thus, could foster anti-skills, and this model contains natural rubber latex which can trigger latex sensitivities and potentially life-threatening allergic reactions in healthcare workers; and
  • Sawbones Humerus, Plastic Cortical Shell, Left ($42.00 USD) because these models do not provide the tactile fidelity necessary to develop the skills to prevent plunging through the far cortex.[49][50][51][45]

Not Made With Natural Rubber Latex[edit | edit source]

Instead of using conventional rubber latex bands glued to re-attach artificial bone fracture fragments, the Humeral Shaft Transverse Fracture Simulator uses inexpensive, locally available, and easy to apply clear cellophane to encapsulate displaced fracture fragments in a simulated soft-tissue envelope.[52] Using cellophane, a material that is not made with natural rubber latex, reduces the risk of triggering latex sensitivities and potentially life-threatening allergic reactions in healthcare workers.[51]

Eco-Friendly[edit | edit source]

All of the module's 3D printed bone simulation models are made from polylactic acid (PLA), a biorenewable, biodegradable, and minimally off-gassing thermoplastic.[53][54][55][56][57][58]

Cruelty-Free[edit | edit source]

Our 3D printed bone models provide a higher fidelity, hygienic, and humane training alternative to using live animal models or mammal cadaveric bones which makes them suitable for the 1.2 billion followers of Hinduism, over 520 million followers of Buddhism, 4.5 million followers of Jainism, and ethical vegans who refrain from using any animal products.[59][60][61][62]

No animal should be harmed from using this training module in accordance with the principles of ahimsa (non-violence or non-injury to all living beings), no killing of any living being under the Right Action Factor of The Eightfold Path of Buddhism, and the recognition of consciousness of all mammals outlined in The Cambridge Declaration on Consciousness.[60][61][63][64]

Equity[edit | edit source]

To make global surgical care equitable, then surgical training (including simulation models) for the Global South must be equivalent in quality to the Global North. This module gives surgical practitioners in LMICs access to open-source, affordable, high fidelity, locally reproducible 3D printed bone simulation models that are comparable to state-of-the-art, quality-tested artificial bone products that are available in high income countries.[45][52]

To advance surgical education and care in LMICs, surgical simulation training must be standardized to monitor performance and clinical outcomes. Providing standardized surgical simulation training requires using reproducible simulators. This module provides high fidelity, 3D printed bone models that can be locally reproduced in any country with an inexpensive, single extruder, fused deposition modeling desktop 3D printer with a minimum build volume Z height of 210 mm, such as the open-source Creality Ender 3 that costs $189 USD.[32] This Appropedia module and our open-source, high fidelity, locally reproducible 3D printed bone simulators can empower unrestricted access to standardized, self-assessed orthopedic surgical simulation training around the world.

Targeted Feedback[edit | edit source]

The transparent cellophane that is wrapped around the Humeral Shaft Transverse Fracture Simulator and simulates the overlying periosteum will permit the learner to visually inspect and confirm that the self-drilling Schanz Screws are properly positioned along the humeral diaphysis and did not perforate the far cortex for the self-assessment framework.

Drawbacks of Traditional Approaches[edit | edit source]

According to the Global Surgical Training Challenge Discovery Awards: Mentoring Programme Handbook - March 2021, "anti-skills are clinically irrelevant skills that the simulator teaches that need to be unlearned when the clinician attempts to transfer what they have learned over to a real clinical scenario," and "[a]t its most fundamental level, anti-skills means incorrect or irrelevant technique, approach and methodology developed or reinforced as a result of using simulation."

During bicortical drilling, the surgeon adjusts drilling direction, speed and applied force to minimize plunge depth.[25] Drilling forces are influenced by cortical thickness, bone site, patient age, and bone mineral density.[26] Low fidelity simulators that do not accurately replicate human cortical bone hardness, and age- and gender-specific cortical thicknesses of humeral diaphyseal sites could foster anti-skills for bicortical drilling in learners. 100% of the orthopedic surgeons (n = 5) we surveyed agreed or strongly agreed that training on high fidelity simulators that accurately replicate human cortical bone hardness will translate into improved plunge depths when performing bicortical drilling on patients compared to low fidelity simulators.

Alternative approaches to orthopedic surgery simulation training include (in order of increasing fidelity): virtual reality simulators, DIY bone simulators, like the Fundamentals of Orthopedic Surgery (FORS) simulator, animal models, synthetic bones, and cadaver laboratories.[65][66][45][49][50][52]

Virtual reality simulators can be expensive and do not provide haptic or acoustic feedback for bicortical drilling skills training.

Low-cost DIY bone simulation models can be time-consuming to prepare and can vary widely in fidelity. This makes it impossible to provide standardized simulation training and to obtain objective, generalizable evaluation data to verify that the user's learnings will directly translate into the safe, clinical performance of bicortical drilling and external modular fixation procedures and will not foster the development of anti-skills.

The FORS simulator can be built from supplies purchased at a local hardware store.[66] However, the FORS Simulator uses low-fidelity polyvinyl chloride (PVC) hollow pipes which:

  1. do not recreate bone contours so the learner is unable to identify anatomic landmarks for proper positioning of external fixation pins into safe zones of the humerus, avoiding having the pins enter a joint cavity, or verifying post-fixation fracture alignment
  2. do not simulate cancellous bone
  3. are not available in accurate cortical thicknesses or cross-sectional shapes which could foster the development of anti-skills for bicortical drilling
  4. are made from vinyl chloride, an industrial carcinogen, and contain small amounts of phthalates, which are endocrine disrupting chemicals, and
  5. do not readily biodegrade and thus, contribute to the rising global levels of plastic waste in landfills, microplastics in oceans and atmosphere, and nanoplastics in the environment.[67][68][69][70][71][72][73][74][75][76][77]

Animal bones do not accurately simulate the length of human bones which would prevent learners from using the correctly sized orthopedic surgical hardware during simulation training.[78] Animal bones also do not have realistic human cortical thicknesses or cross-sectional shapes and this could foster the development of anti-skills for bicortical drilling.[79][80] Studies have shown significantly different drilling temperature values (which correlate with drilling energy and drilling force) in animal versus human bones.[26][79][80]  Animal bones also require the slaughtering of sentient beings and additional time-consuming preparation for use in simulation training and cannot reliably reproduce different fracture patterns to permit standardized orthopedic surgical skills training.[64]

Artificial bones are inaccessible in low to middle income countries due to long delivery times and high import costs from customs dues and processing fees because they are not produced locally.[45][49][50][52]

There is limited or no practitioner access to costly cadaver labs outside of training centers.

Acknowledgements[edit | edit source]

This work is funded by a grant from the Intuitive Foundation. Any research, findings, conclusions, or recommendations expressed in this work are those of the author(s), and not of the Intuitive Foundation.

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