Source
- Bas Wijnen, Emily J. Hunt, Gerald C. Anzalone, Joshua M. Pearce, 2014. Open-source Syringe Pump Library, PLoS ONE 9(9): e107216. doi:10.1371/journal.pone.0107216 open access
- The source code for the linear actuator and pump server are housed here: https://github.com/mtu-most/linear-actuator
- You will need MOST SCAD library files found here: https://github.com/mtu-most/most-scad-libraries
- For example STL files see https://www.youmagine.com/designs/syringe-pump
Abstract
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This article explores a new open-source method for developing and manufacturing high-quality scientific equipment suitable for use in virtually any laboratory. A syringe pump was designed using freely available open-source computer aided design (CAD) software and manufactured using an open-source RepRap 3-D printer and readily available parts. The design, bill of materials and assembly instructions are globally available to anyone wishing to use them. Details are provided covering the use of the CAD software and the RepRap 3-D printer. The use of an open-source Raspberry Pi computer as a wireless control device is also illustrated. Performance of the syringe pump was assessed and the methods used for assessment are detailed. The cost of the entire system, including the controller and web-based control interface, is on the order of 5% or less than one would expect to pay for a commercial syringe pump having similar performance. The design should suit the needs of a given research activity requiring a syringe pump including carefully controlled dosing of reagents, pharmaceuticals, and delivery of viscous 3-D printer media among other applications.
Key Words
open source hardware, open source scientific hardware
Materials and Tools
Note: This page describes the mechanical build. Please refer to the paper for the electronics.
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Procedure
- Secure motor into the motor end using 4 M3 washers and 4 M3 x 20mm socket head cap screws.
- Insert the 2 metal rods into motor end, then secure them in place with 2 M3 nuts and 2 M3 x 10mm socket head cap screws.
- Insert threaded rod into the coupler halfway, the other half should be on the motor, secure it.
- Hollow out the two ends of the carriage, with a handheld drill bit or knife to make a hole in the plastic.
- Snap the linear bearings into place on the hollowed out ends of the carriage. Then insert an M5 nut into the nut-trap on the bottom of the carriage.
- Attach the base of the Plunger holder to the carriage with 2 M3 nuts and 2 M3 x 10mm socket head cap screws.
- Slide the carriage onto the threaded rod and make sure the two metal rods fit into the linear bearings.
- After the carriage is midway down the threaded rod, thread two M5 nuts onto the threaded rod.
- Insert the two bearings into the circular slots in the idler end.
- Now slide the idler end onto the rods and secure it with two more M5 nuts on the end of the threaded rod. Push the two nuts already on the rod up to the idler end to secure it.
- Insert the syringe body into the body holders, then slide the plunger into the base of the plunger holder.
- Using four M3 x 40mm bolts, four M3 washers, and four M3 nuts secure the two holding pieces to the idler end of the pump. Put two nuts it the top of the holder closer to the carriage and two nuts in the bottom of the holder against the idler end.
- Insert the tab of the plunger holder on top of the plunger to secure it to the pump and prevent slipping when in use.
Controller: Connection and Calibration
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- Plug the motor into the raspberry pi. If the motor is plugged in the wrong way the pump will push when its told to pull. NOTE: Do not plug and unplug the motor from the pi if the pi is plugged in to a power source.
- Using a mini-USB adaptor plug the raspberry pi into the computer.
- Plug an ethernet cable into the raspberry pi, then connect it to the Netgear wireless router. Then connect the router to the computer with another ethernet cable.
- Plug everything into an outlet and turn on the router. Look to see that your computer recognizes the network. Once it does, switch over to that network and open up your web browser. Type in the address bar: pi.local:8080. NOTE: This is only the address if a version of Linux is in use. We have no practical way to get the address on Windows or Mac, however it does work on Windows and Mac if the name can be obtained.
- The site that is now opened is the pump control interface. Set it to a lower speed, then pull the syringe out slightly past a big marker. Then using tiny steps, push the syringe to the bigger marker so the plunger is exactly on the mark. Then push it 50 mm, and record how many milliliters it moves. Then divide the number of milliliters it went by the number of millimeters you pushed it and plug that number into the calibration window.
See also
- Open-source Lab
- Building research equipment with free, open-source hardware
- Open source science
- Open source optics
- Open source 3-D printing of OSAT
- Open-source hardware
- Syringe pump literature review
Coupled Initiatives
- Open pump -Help to make better devices for healthcare and lab environments
- Open Syringe Pump on Hackaday by naroom - Arduino controlled
- Will Patrick's OS syringe pump at MIT
- Trial database uploads:
In the News
- Science Just Got Cheaper (and Faster): Design Library Lets Researchers Print their Own Syringe Pumps - Michigan Tech News
- Doctors Could 3D Print Their Own Tools For a Fraction of the Cost - Gizmodo, Gizmodo India, Gizmodo Australia, USA News
- 3D Printed Syringe Pumps are Perfect for Cash Strapped Scientists - Motherboard
- 3D Printable Syringe Pump Design Lowers Lab Costs - Med Device
- 3D-printed syringe pumps could cut the cost of scientific research - Gizmag
- 3-D printing leads to another advance in make-it-yourself lab equipment - Phys.org
- Make-it-yourself lab equipment with 3-D printing- Nanowerk
- 3D-printed syringe pumps could cut a cost of systematic research- World News Source
- Researchers could now 3D print their own syringe pumps using a RepRap - 3Ders
- Doing science just got cheaper -- and faster - Science Codex
- RepRap: Open Source Lab Equipment Makes Science Cheaper - And Faster - Science 2.0
- 3D Printed Syringe Pumps Cost a Mere Fraction of Traditional Pumps - 3D Print
- "Another day, another phenomenal addition to the list of practical, hype-less, real, tangible, 3D printable tools that are bound to bring on some welcome changes. This time, it’s the scientific community that can sing praises and raise their glasses as they’re about to reap the benefits – and save a bundle – on 3D printed syringe pumps."
- Doing science just got cheaper -- and faster - ECN
- Doctors Can 3D Print Syringe Pumps for a Pittance Now - Softpedia
- 3DP Leads to Another Advance in DIY Science Equipment - Engineering.com
- The medical world could become much cheaper thanks to 3D printing Inside 3DP
- 3D-printed syringe pumps could cut the cost of scientific research -- Electronic Engineering Journal
- Michigan Tech Offers Free Designs For 3D Printing Lab Gear - Technology Century
- 3D-Printed Lab Equipment Stretches Research Budgets- Polymer Solutions Newsblog, Lab Manager
- New open source designs make lab work affordable - The Lode
- Science just got cheaper (and faster) - Today's Medical Developments
- Open-Source Syringe Pump Library - Replicator World
- Open source syringe pump - Raspberrypi.org
- Open source syringe pump - FreeIO.org
- How 3D Printing Can Reduce Medical Expenses - Nation Swell
- A TEMPLATE LIBRARY ALLOWS RESEARCHERS TO PRINT IN 3D, THEIR OWN SYRINGE PUMPS - InfoHighTech (France)
- Open Source Hardware soll durch Kosteneinsparung Medizin revolutionieren - 3Druck (Germany)
- 3D printed syringe pump - What Next (Poland)
- Injection pump open source 3D printing model library to help scientists provincial money - Maker8 (China)
- 3D打印,模型库,注射泵,开源 - 中关村在线办公打印频道 - oa.zol.com.cn (Zhongguancun Online (zol.com.cn) - the world's first Chinese technology portal, Greater China's most commercially valuable IT professional portal.)