Open Source Bottle Roller Literature review

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Background Information[edit | edit source]

Bottle Rollers are used to roll different sizes and types of roller bottles at a rate of 1-80rpm. The roller bottle that are placed on the Bottle Roller are used for growing or storing cell cultures while being rotated in a heated environment. Bottle Rollers can also be used for a wide verity of mix different solutions together, and the amount of leaching that can form different materials. The typical price range for a Bottle Roller bought online can be in excess of $950 up to $2,000 for a single level Bottle roller system.

Applications[edit | edit source]

Bottle Rollers are used for a wide variety of different application that are implemented in many different fields of the scientific community. Application for bottle rollers have been used for creating cell cultivation, material leaching, sediment washing, roller bottle drying, and many more application. Bottle Rollers are able to be used for almost anything that involves something being mixed or rotated in a bottle for any amount of time in different environment's.

Design Specification[edit | edit source]

The Bottle Roller should be able to meet the following design specification:

  • Operation speed range of 1-80 RPM.
  • Maximum Roller Bottle diameter 120 millimetres
  • Operation Time range 1-999 minutes or continuous function
  • Minimum of 2 Roller Bottle capacity

Design Concept Drawing[edit | edit source]



Companies Contacted[edit | edit source]

  • Thomas Scientific
  • Globalindustrial

List of Search Terms[edit | edit source]

  • Bottle Roller
  • Bottle Roller Machine
  • Open Source Bottle Roller
  • Open Source Tube Roller
  • Bottle Roller Operation
  • How Bottle Rollers are made.
  • Bottle Roller Manufacturers.
  • Automated Bottle Roller
  • Building A Bottle Roller

Product Specs[edit | edit source]

ThermoFisher Scientific[edit | edit source]

  • Speed Range 1 to 80rpm
  • Temperature Range (Metric) 4° to 60°C (Operating)
  • Load Bearing Capacity (English) 14.3 lb.
  • Load Bearing Capacity (Metric) 6.5kg
  • Height (English) Exterior 2.8 in.
  • Length (English) Exterior 14.2 in.
  • Width (English) Exterior 14.9 in.
  • Height (Metric) Exterior 72mm
  • Length (Metric) Exterior 360mm
  • Width (Metric) Exterior 378mm
  • Voltage AC100V to 240V
  • Shipping Weight (English) 14.3 lb.
  • Shipping Weight (Metric) 6.5kg
  • Hertz 50/60Hz
  • Wattage 10W
  • Diameter (English) Roller 1.1 in.
  • Diameter (Metric) Roller 28mm
  • Display LED Roller Speed Display
  • Max. Bottle Diameter (English) ≤ 4.72 in.
  • Max. Bottle Diameter (Metric) ≤ 120mm
  • No. of Rollers 6 rollers standard, up to 11 can be added
  • Plug Type USA
  • Relative Humidity ≤ 95%
  • Stackable Two high with optional kit
  • Timer Range 0 to 999 min. or continuous
  • Warranty and Service Offering 2 Years
  • Tolerance ≤ 95% humidity and CO2 resistant
  • Electrical Requirements AC100V to 240V 50/60Hz
  • Dimensions (L x W x H) Exterior 14.2 x 14.9 x 2.8 in. (360 x 378 x 72mm)
  • Type Rollers
  • Unit Size Each

Globalindustrial-Thermo Scientific™[edit | edit source]

  • MANUFACTURERS PART NUMBER 88881003
  • LENGTH INCHES 14-1/4
  • WIDTH INCHES 14-7/8
  • HEIGHT INCHES 2-13/16
  • WEIGHT LBS 14.3
  • DESCRIPTION Digital Bottle/Tube Roller
  • CAPACITY Up to 120mm (4.72") Diameter Bottle
  • TEMPERATURE RANGE 4° to 60°C (Operating)
  • VOLTAGE 100-240V
  • HERTZ 50/60Hz
  • TYPE Rollers
  • PACKAGE QUANTITY 1
  • CERTIFICATIONS CE, cCSAus
  • LIMITED WARRANTY 2 Years
  • SPEED RANGE 1 to 80 RPM
  • MAX LOAD 14.3 lbs.
  • TIMER 0 to 999 min. or Continuous


References[edit | edit source]

ThermoFisher Scientific Bottle/Tube Roller[edit | edit source]

  • Product Pricing
  • Product applications
  • Product Specs

Thomas Scientific 120V Benchtop Roller Culture Apparatus Small[edit | edit source]

  • Product Pricing
  • Product Application
  • Product Design

Globalindustrial Thermo Scientific Digital Bottle/Tube Roller[edit | edit source]

  • Bottle Roller dimensions.
  • Operation Temperature Range.
  • Bottle Roller Pricing.

Cole-Parmer lbi Scientific Low-Profile Bottle Roller[edit | edit source]

  • Product Priceing
  • Bottle Roller capacity.

Essa BR-Series Bottle Rollers[edit | edit source]

  • Different Bottle Roller Design

Made-in-Chine Yosion: Bottle/Tube roller Manufacturer Bottle Grinding Crusher[edit | edit source]

  • Larger Scale Bottle Roller
  • Different Design
  • Pricing

Technical Development Corporation Bottle Roller Medical[edit | edit source]

  • Multiple Stacked Bottle Roller
  • Medical Applications

Journal of Hazardous Materials[edit | edit source]

  • Application

LLPM University of Lampung[edit | edit source]

  • Medical Application

NISCAIR[edit | edit source]

  • Geological application
  • Mineral Separation

Production of influenza H1N1 vaccine from MDCK cells[edit | edit source]

  • Medical application

Inter-Laboratory Comparison of Leaching Methods[edit | edit source]

  • Serial Batch Leaching Procedure

Dietary Exposure to 2-Aminoanthracene [edit | edit source]

  • Basal diet blending using bottle roller

Europe PMC Pilot-Scale Preparation of clinical-grade third generation Lentivirus[edit | edit source]

  • Cell cultures for Fibra-Cel sheet carrier

Insecticide Resistance Evaluation of Culex Quinquefasciatus[edit | edit source]

  • Roller Bottle drying application

Diagnostic doses and times for Phlebotomus papatasi and Lutzomyia longipalpis sand flies[edit | edit source]

  • Coating roller bottles with insecticide using a bottle roller

Examination of moisture sensitivity of aggregate–bitumen bonding strength using loose asphalt mixture and physico-chemical surface energy property tests[edit | edit source]

  • Aggregate-mixture mixing using bottle roller

Determining Optimum Wet Milling and Leaching Parameters for Maximum Recovery of Gold[edit | edit source]

  • Bottle Rolling leach testing
  • Bottle roller operation duration

Identification and environmental significance of organic pollutants and heavy metal contaminants found in water and sediments collected from the Matanza-Riachuelo Basin, Argentina 1997 [edit | edit source]

  • Solvent mixing with extraction samples

Gluten contamination in the Canadian commercial oat supply[edit | edit source]

  • Homogenization mixing of composite samples

Automated Bottle Roller[edit | edit source]

  • Bulleted list item* Concept design for 3D printed Bottle Roller.

Identification of Sediment Sources in the Fitzroy River Basin and Estuary, Queensland, Australia[edit | edit source]

  • Use for sediment washing in roller bottles.


Bibliography[edit | edit source]

“120V Benchtop Roller Culture Apparatus Small.” Accessed September 10, 2020. https://www.thomassci.com/Equipment/Roller-Bottle-Apparatus/_/Small-Bottle-Roller-Culture-System?q=Roller%20Bottle%20Apparatus.

“Automated Bottle Roller | NIH 3D Print Exchange.” Accessed September 16, 2020. https://3dprint.nih.gov/discover/3dpx-012419.

Technical Development Corporation. “Bottle Roller Medical - TDC.” Accessed September 13, 2020. https://technicaldevelopment.com/bottle-roller-medical/.

“Bottle/Tube Roller.” Accessed September 8, 2020. https://www.thermofisher.com/order/catalog/product/88881003.

Boudreau, M. D., H. W. Taylor, D. G. Baker, and Jay C. Means. “Dietary Exposure to 2-Aminoanthracene Induces Morphological and Immunocytochemical Changes in Pancreatic Tissues of Fisher-344 Rats.” Toxicological Sciences 93, no. 1 (September 1, 2006): 50–61. https://doi.org/10.1093/toxsci/kfl033.

D, Duan, Ji Y, Zhou M, and Gao J. “[Pilot-Scale Preparation of Clinical-Grade Third Generation Lentivirus].” Sheng Wu Gong Cheng Xue Bao = Chinese Journal of Biotechnology 35, no. 7 (July 1, 2019): 1307–16. https://doi.org/10.13345/j.cjb.190127.

Denlinger, David S., Joseph A. Creswell, J. Laine Anderson, Conor K. Reese, and Scott A. Bernhardt. “Diagnostic Doses and Times for Phlebotomus Papatasi and Lutzomyia Longipalpis Sand Flies (Diptera: Psychodidae: Phlebotominae) Using the CDC Bottle Bioassay to Assess Insecticide Resistance.” Parasites & Vectors 9, no. 1 (April 15, 2016): 212. https://doi.org/10.1186/s13071-016-1496-3.

“Essa-Br-Series-Bottle-Rollers.Pdf.” Accessed September 10, 2020. https://flsmidth-prod-cdn.azureedge.net/-/media/brochures/brochures-products/sampling-preparation-and-analysis/essa-br-series-bottle-rollers.pdf?rev=392d54a1-7435-497c-84c0-bff06683ae35.

Guajardo, Milena C., Mariah L. Scott, Lee Noel, Broox Boze, and Janet C. McAllister. “Insecticide Resistance Evaluation of Culex Quinquefasciatus, 2017.” Arthropod Management Tests 44, no. 1 (January 1, 2019). https://doi.org/10.1093/amt/tsz012.

Hesbach, Peter, Michel Beck, Matt Eick, W Lee Daniels, Amie Greiner, David J Hassett, and Loreal V Heebink. “Inter-Laboratory Comparison of Leaching Methods,” n.d., 28. Hlabangana, Nkosikhona, Nonhlanhla G Mguni, Siboniwe Bhebhe, Gwiranai Danha, and Joel Tshuma. “Determining Optimum Wet Milling and Leaching Parameters for Maximum Recovery of Gold” 5, no. 4 (2017): 13.

Made-in-China.com. “[Hot Item] Bottle /Tube Roller Manufacturer Bottle Grinding Crusher.” Accessed September 13, 2020. https://yosionlabtech.en.made-in-china.com/product/KSymjThJAVpN/China-Bottle-Tube-Roller-Manufacturer-Bottle-Grinding-Crusher.html.

“Ibi Scientific Low-Profile Bottle Roller; 90-240 VAC, 50/60 Hz from Cole-Parmer.” Accessed September 11, 2020. https://www.coleparmer.com/i/ibi-scientific-low-profile-bottle-roller-90-240-vac-50-60-hz/3620203?PubID=UX&persist=true&ip=no&gclid=EAIaIQobChMI2Ib61M7h6wIVAr7ACh1RyAmMEAQYBSABEgJchfD_BwE.

Koerner, T. B., C. Cléroux, C. Poirier, I. Cantin, A. Alimkulov, and H. Elamparo. “Gluten Contamination in the Canadian Commercial Oat Supply.” Food Additives & Contaminants: Part A 28, no. 6 (June 1, 2011): 705–10. https://doi.org/10.1080/19440049.2011.579626.

Liu, Yawen, Alex Apeagyei, Naveed Ahmad, James Grenfell, and Gordon Airey. “Examination of Moisture Sensitivity of Aggregate–Bitumen Bonding Strength Using Loose Asphalt Mixture and Physico-Chemical Surface Energy Property Tests.” International Journal of Pavement Engineering 15, no. 7 (August 9, 2014): 657–70. https://doi.org/10.1080/10298436.2013.855312.

Park, Donghee, Chi Kyu Ahn, Young Mi Kim, Yeoung-Sang Yun, and Jong Moon Park. “Enhanced Abiotic Reduction of Cr(VI) in a Soil Slurry System by Natural Biomaterial Addition.” Journal of Hazardous Materials 160, no. 2 (December 30, 2008): 422–27. https://doi.org/10.1016/j.jhazmat.2008.03.044.

Raju, P. V. Sunder. “Comparison of Different Extraction Methods to Determine Gold in Geological Samples.” JSIR Vol.65(01) [January 2006], January 2006. http://nopr.niscair.res.in/handle/123456789/4803.

“Riacheulo_tech_note_05-98.Pdf.” Accessed September 14, 2020. https://www.greenpeace.to/publications/Riacheulo_tech_note_05-98.pdf. Suharso, Suharso, Buhani, Suripto D. Yuwono, and Tugiyono Tugiyono. “Inhibition of Calcium Carbonate (CaCO3) Scale Formation by Calix [4] Resorcinarene Compounds.” Desalination and Water Treatment, no. 68 (March 1, 2017): 32–39.

Sun, Bo, XiangHui Yu, Wei Kong, Shiyang Sun, Ping Yang, Changlin Zhu, Haihong Zhang, et al. “Production of Influenza H1N1 Vaccine from MDCK Cells Using a Novel Disposable Packed-Bed Bioreactor.” Applied Microbiology and Biotechnology 97, no. 3 (February 1, 2013): 1063–70. https://doi.org/10.1007/s00253-012-4375-7.

“The Commonwealth Scientific and Industrial Research Organisation.” Current Biology 7, no. 3 (March 1997): R126. https://doi.org/10.1016/S0960-9822(97)70976-X.

Global Industrial. “Thermo Scientific Digital Bottle/Tube Roller, 14.3 Lbs. Max Load, 100-240V 50/60Hz.” Accessed September 10, 2020. https://www.globalindustrial.com/p/medical-lab/laboratory-equipment/tube-rotators/digital-bottle-tube-roller-14-3-lbs-max-load-100-240v-50-60hz.