TissueDB/Simulators/VesselBox Vessel Ligation Trainer (Hu)
General Information
The VesselBox Vessel Ligation Trainer is a low-cost open-surgery simulator developed at the University of Virginia for graduating fourth-year medical students and incoming PGY-1 surgery residents preparing for open abdominal procedures (Hu et al. 2015, Journal of Surgical Education;[1] Hu et al. 2015, Journal of Surgical Research[2]). The construct uses a four-sided pine box, a vessel-mounting device, and a disposable latex glove finger as the vessel substitute. A trainee performs proximal and distal vessel control, division between forceps with Mayo scissors, and tied ligation using 3-0 silk, while a surgical assistant maintains opposing forceps and releases each in turn at the trainee's prompt. The construct sits in a deep, vision-restricted compartment by design, replicating the difficulty of controlling a vascular pedicle in a confined abdominal cavity. The simulator was assessed in a peer-reviewed validation study across four skill tiers (medical students, surgical interns, residents, and faculty) with significant stratification on both checklist and OSATS Global Rating Scale metrics, and the same construct was used in a Cusum-guided adaptive curriculum that demonstrated pre/post improvement on independent cadaver post-tests. Substitute mount designs and full per-row recipe details follow.
| Field | Details |
|---|---|
| General Information | Source anatomy: the latex glove finger represents a generic vascularised tubular structure for ligation practice. Hu et al. 2015 describe the model as imitating larger vessels and bowel mesentery well, and smaller, more friable vessels less well.[1] Tested-and-rejected vessel substitutes prior to selecting latex glove fingers: penrose drains, flexible intravenous tubing, and silicone tubing — none replicated the deformable-yet-elastic behaviour of a vessel under tension required for tying a knot to a positive ligature.[1] Surgical instruments used per session: two curved Kelly forceps, Mayo scissors, and 3-0 silk ties. Suture source per the original study: Hefei Fast Nonwoven Products Co, Anhui, China, at USD 0.10 per silk tie in 2014 (≈ USD 0.14 in 2026[3]). Camera framing during evaluation sessions was deliberately limited to the simulator and the participants' forearms, blinding raters to participant identity and skill tier.[1][2] The construct sits within a confined-field family of low-cost open-surgery trainers and pairs naturally with a Cusum-guided adaptive curriculum.[2] |
| Features and Basic Operation | Not stated in source |
| Current Development Status | Peer-reviewed validated. The construction paper (Hu et al. 2015, J Surg Educ) is tagged as a Validation Study by PubMed and reports a four-tier evaluation across N = 35 participants: 16 fourth-year medical students, 6 PGY-1 surgical interns, 8 PGY-2/3 surgical residents, and 5 surgical faculty.[1] Stratification was statistically significant (p < 0.001) on both the procedure-specific checklist (median scores 4.83 / 5.83 / 7.33 / 7.67 from students through faculty) and the OSATS Global Rating Scale (median scores 2.29 / 2.38 / 4.43 / 4.76).[1] Internal consistency was reported as Cronbach's α = 0.71 for the checklist and α = 0.96 for the GRS.[1] Subjective acceptance among interview respondents (N = 15) was high: 14 of 15 (93%) felt the model closely emulated intraoperative processes, and all 15 (100%) felt the model would be useful in preparing junior trainees for open surgery.[1] The curriculum paper (Hu et al. 2015, J Surg Res) reports pre/post improvement on the same construct: GRS 2.29 → 3.23 (p < 0.001), checklist 4.83 → 7.33 (p < 0.001), and procedure speed 128.2 → 97.5 seconds (p = 0.001), with a fresh human cadaver post-test (short gastric artery, mesenteric artery branch, or extremity venous branch; friable strands of breast tissue used as a surrogate when no vessel was available).[2] Operator-experienced critique recorded in Hu et al. 2015 (J Surg Educ): one participant felt that proximal tie ligation should precede vessel division — a published construct critique to consider in future curriculum refinement.[1] IRB: University of Virginia IRB-SBS protocol #2013-0457-00.[1][2] |
| Estimated Build Time and Cost | Per-model construction is a one-off cabinetry job (cut, fasten, install mounts) followed by per-session glove-finger mounting at less than 30 seconds per mount, with two ligation attempts per mounted glove finger.[1] An adaptive curriculum session per Hu et al. 2015 (J Surg Res) averaged 21.8 minutes (IQR 19.5–27.7), with individual learners requiring 8 to 16 practice attempts to reach Cusum-defined proficiency.[2], Total construction cost reported by Hu et al. 2015: USD 30 per model in 2014 (≈ USD 42 in 2026[3]), against an explicit budgetary parameter of less than USD 100 per model.[1] Per-attempt consumable cost: less than USD 0.20 per attempt in 2014 (≈ less than USD 0.28 in 2026[3]). Total study cost (one constructed simulator plus 35 evaluation sessions): less than USD 50 in 2014 (≈ less than USD 69 in 2026[3]). Commercial open-vessel-ligation kits available from overseas were quoted at USD 200–500 each (2014) by Hu et al., which the VesselBox was explicitly positioned to undercut.[1] |
| Specialized Tools and Equipment | Per-session surgical instrument tray: two curved Kelly forceps, Mayo scissors. Construction tooling: standard cabinetry tools (saw, drill, screwdriver). No 3D printer is required for the published construct or for Substitute Design A below.[1] |
| Version | Not stated in source |
| Development Team Contact Information | Yinin Hu (yh9b@virginia.edu, first author); Sara K Rasmussen (skr3f@virginia.edu, corresponding author). Department of Surgery, University of Virginia School of Medicine. Builders seeking exact replication of the published proprietary mount are encouraged to contact the authors directly, as the mount geometry is not described in either published paper.[1] |
Tissues
| Tissue | Qty | Material | Cost | Notes |
|---|---|---|---|---|
| Blood vessel | 1 finger per 2 ligations | Disposable latex surgical glove | Negligible per attempt (≈ USD 0.14/attempt in 2026 inclusive of silk tie[3]) | Glove finger mounted between two clamps spanning the open top of the box, ~20–25 cm apart. Hu et al. 2015 selected disposable latex surgical gloves after testing penrose drains, flexible intravenous tubing, and silicone tubing — the glove finger was deformable enough to clamp and tie yet elastic enough to require steady tension for a successful ligature.[1] The construct represents larger vessels and vascularised tissues (e.g. bowel mesentery) well, and smaller, more friable vessels less well.[1] |
Structural Parts
| Part Name | Qty | Material | Cost | Notes |
|---|---|---|---|---|
| Pine wood box (four-sided) | 1 | Pine offcut or dimensional pine | Included in USD 30 fixed build (2014; ≈ USD 42 in 2026[3])[1] | Hu et al. 2015 (J Surg Educ) describe the construct as a "four-sided box created from pine wood to simulate a confined abdominal compartment". The earlier curriculum paper describes the same construct as a "three-sided box" — the construction paper is authoritative for build description. Box dimensions are not specified by the authors; build to a depth and width that restricts visualisation while permitting two-handed instrument access.[1] |
| Vessel mounting device (proprietary in source) | 1 paired set | See Build Instructions §2 below — TissueDB-suggested binder-clip substitute design | ~USD 3 (2026, Substitute Design A; not part of the published proprietary mount) | Hu et al. 2015 describe the original mount as "a proprietary vessel mounting device … secured to the base of the replicated surgical field". The mount geometry, tensioning mechanism, and material are not described in either the construction paper or the curriculum paper.[1] Build Instructions §2 below specifies a TissueDB-suggested binder-clip substitute (Substitute Design A); this is not a replica of the published proprietary design and may produce different clamping force and tension. Builders seeking exact replication should contact the corresponding author Sara K Rasmussen (skr3f@virginia.edu) or first author Yinin Hu (yh9b@virginia.edu). |
| 3-0 silk suture | 1 per ligation (2 per mounted glove finger) | 3-0 braided silk | USD 0.10 each in 2014 (Hefei Fast Nonwoven Products Co, Anhui, China); ≈ USD 0.14 each in 2026[3] | Hu et al. 2015 specify 3-0 silk ties throughout the protocol. Per-attempt suture cost is the dominant per-attempt consumable, supporting the published per-attempt cost of less than USD 0.20 in 2014.[1] |
| Curved Kelly forceps | 2 | Surgical-grade stainless steel | Reusable; not itemised by Hu et al. 2015 | One forceps applied by the trainee for proximal control, one by the surgical assistant for distal control. Reusable across sessions; no per-session cost.[1] |
| Mayo scissors | 1 | Surgical-grade stainless steel | Reusable; not itemised by Hu et al. 2015 | Used for vessel division between proximal and distal forceps. Reusable across sessions; no per-session cost.[1] |
Build Instructions
Phase 1: Construct the four-sided pine box
- Cut four pine boards to form the walls of a deep, four-sided box because Hu et al. 2015 specify a "four-sided box created from pine wood" to simulate a confined abdominal compartment.[1] Box dimensions are not specified in either published paper — choose a depth and base width that restrict visualisation of the working field while still permitting two-handed instrument access and a vessel mount span of approximately 20–25 cm. A starting reference (TissueDB-suggested, not source-specified) is approximately 30 × 20 × 15 cm internal.
- Fasten the four walls together using wood screws or nails, ensuring the open top permits clear instrument access and that the construct sits stable on a flat workbench surface.
- Sand any rough edges that might catch instruments or sutures during a session.
- Confirm the box is rigid enough to resist deformation under the tension required to tie a 3-0 silk ligation against a glove-finger vessel substitute.
Phase 2: Install the vessel mounting device — TissueDB-suggested Substitute Design A (binder-clip mount)
Important note: the original VesselBox uses a "proprietary vessel mounting device" (Hu et al. 2015) that is not described in either published paper.[1] The design below is a TissueDB-suggested substitute, not a replica of the published mount, and may produce different clamping force and tension. Builders seeking exact replication of the published design are encouraged to contact the corresponding author Sara K Rasmussen (skr3f@virginia.edu, University of Virginia School of Medicine) or first author Yinin Hu (yh9b@virginia.edu).
- Cut two pine blocks to approximately 50 × 30 × 15 mm from offcuts because they will form the mounting platforms for the binder-clip clamps on either side of the box base.
- Drill two 3 mm pilot holes through the wide face of each pine block, approximately 30 mm apart, because these holes will receive the wood screws affixing each binder-clip to its block.
- Clamp each large binder-clip arm in a vice and drill a fine matching hole (approximately 2 mm) through each arm-shaft because the binder-clip must be screw-fastened to its pine block, not adhesive-fastened, to withstand tying tension.
- Screw each binder-clip to its pine block using two 25 mm wood screws, one screw per arm-shaft hole into the block face.
- Position the two clip-block assemblies on opposite walls of the box base, approximately 20–25 cm apart, with the clip jaws facing each other across the open compartment.
- Drill two pilot holes through the bottom of each clip-block assembly into the box base, and affix each block with two more 25 mm wood screws.
- Confirm a glove-finger pinched between the two clip jaw sets is held under steady tension during a test ligation, and that slips do not occur until intentional release.
Limitations of Substitute Design A (build-phase note): binder-clip clamping force is not equivalent to the published proprietary mount's tension. Some experimentation may be required to find the optimal glove-finger length and tension for a given trainee population. Glove fingers are held by friction at the binder-clip jaws; slips can occur during high-force ligation and require reseating between attempts.
Phase 3: Glove mounting and per-session reset
- Cut a finger from a fresh disposable latex surgical glove because the glove finger is the vessel substitute and must be discarded after two ligations per Hu et al. 2015.[1]
- Insert one open end of the glove finger between one binder-clip's jaws and release the clip jaws to grip, because the glove finger must be held under tension between the two mounts.
- Repeat on the opposing binder-clip jaws, ensuring the glove finger spans the gap between the two mounts taut and parallel to the box base.
- Confirm the mounting time is less than 30 seconds per mounted glove finger and that the construct permits two ligation attempts per mounted glove finger before disposal, both as specified by Hu et al. 2015.[1]
- Replace the used glove finger and any soiled silk ties between learners, then check the binder-clip mounts and pine box for rigidity and undamaged condition before the next session.
Phase 4: Adaptive (Cusum-guided) curriculum mode (optional)
- Set the Cusum acceptable failure rate at 5% and the unacceptable failure rate at 20% because Hu et al. 2015 (J Surg Res) specify these decision parameters for surgical-skill acquisition Cusum analysis on this construct.[2]
- Set the Type I error rate at 10% and the decision interval h₀ at 1.41 because these were the parameters used in the published Cusum-guided curriculum and produced the reported 8 to 16 practice attempts to proficiency.[2]
- Run the trainee through a rolling window of 8 practice attempts because Hu et al. 2015 (J Surg Res) used an 8-attempt window for proficiency assessment.[2]
- Score each attempt against the procedure-specific checklist and the OSATS Global Rating Scale, with camera framing limited to the simulator and the participants' forearms to blind the rater to identity and skill tier.[1][2]
- Plan an average session length of approximately 21.8 minutes (IQR 19.5–27.7 per Hu et al. 2015, J Surg Res) and expect 8 to 16 attempts to reach Cusum-defined proficiency.[2]
- Run an optional fresh human cadaver post-test at the end of curriculum (short gastric artery, mesenteric artery branch, extremity venous branch, or friable strands of breast tissue as a surrogate when no vessel is available) per the published transfer-of-skill protocol.[2]
References
- ↑ 1.00 1.01 1.02 1.03 1.04 1.05 1.06 1.07 1.08 1.09 1.10 1.11 1.12 1.13 1.14 1.15 1.16 1.17 1.18 1.19 1.20 1.21 1.22 1.23 1.24 1.25 1.26 1.27 1.28 Hu Y, Le IA, Goodrich RN, Edwards BL, Gillen JR, Smith PW, Schroen AT, Rasmussen SK. Construct validation of a cost-effective vessel ligation benchtop simulator. Journal of Surgical Education. 2015;72(3):381–388. PMID 25678049. DOI 10.1016/j.jsurg.2014.11.003.
- ↑ 2.00 2.01 2.02 2.03 2.04 2.05 2.06 2.07 2.08 2.09 2.10 2.11 2.12 Hu Y, Goodrich RN, Le IA, Brooks KD, Sawyer RG, Smith PW, Schroen AT, Rasmussen SK. Vessel ligation training via an adaptive simulation curriculum. Journal of Surgical Research. 2015;196(1):17–22. PMID 25796112. DOI 10.1016/j.jss.2015.01.044.
- ↑ 3.0 3.1 3.2 3.3 3.4 3.5 3.6 3.7 U.S. Bureau of Labor Statistics, Consumer Price Index for All Urban Consumers (CPIAUCNS), retrieved from FRED, Federal Reserve Bank of St. Louis. https://fred.stlouisfed.org/series/CPIAUCNS. Accessed 1 May 2026. CPI factor June 2014 (238.343) → March 2026 (330.213) = 1.3854.
| Alternative names | VesselBox; Hu Vessel Ligation Trainer; UVA Vessel Ligation Box |
|---|
| Authors | Arturopelayo |
|---|---|
| License | CC-BY-SA-4.0 |
| Cite as | Arturopelayo (2026). "TissueDB/Simulators/VesselBox Vessel Ligation Trainer (Hu)". Appropedia. Retrieved June 4, 2026. |