FA info icon.svgAngle down icon.svgMedical equipment data
Health topic HIV/AIDS
Health classification Preventative
FA info icon.svgAngle down icon.svgProject data
Location Israel
Status Commercialized
Made No
Replicated No
Instance of Circumcision device
OKH Manifest Download

Problem being addressed[edit | edit source]

Male circumcision has been identified as an effective method to control HIV transmission. However, the conventional clinical procedure requires a skilled medical professional, a sterile facility, and specialized equipment to be safely implemented.

Detailed description of the solution[edit | edit source]

Prepex is a simple, inexpensive device that allows for non-surgical and safe adult male circumcision. It functions by three simple steps. First, after selecting the correct size, the area to be circumcised is marked according to WHO guidelines, and an inner ring is inserted. Next, an elastic ring is painlessly aligned with the inner ring to cut off blood flow to the foreskin. After seven days, the dead foreskin and rings are easily removed.

Designed by[edit | edit source]

  • Design: The device was designed by three Israeli researchers.
  • Marketing: The device is being marketed by CIRC MedTech.

When and where it was tested/implemented[edit | edit source]

Clinical trials were completed in Rwanda in May 2011.

Funding Source[edit | edit source]

Privately funded.

References[edit | edit source]

Peer-reviewed publication[edit | edit source]

Bitega, J. P., Ngeruka, M. L., Hategekimana, T. et al. (2011). Safety and efficacy of the PrePex device for rapid scale-up of male circumcision for HIV prevention in resource-limited settings. J Acquir Immune Defic Syndr 15(58):e127-134.

Bitega, J. P., Ngeruka, M. L., Hategekimana, T. et al. (2011). Safety and efficacy study of the PrePex system for male circumcision. 18th Conference on Retroviruses and Opportunistic Infection, Session 196. Boston, MA.

Hategekimana, T., Bitega, J. P., Ngeruka, M. L. et al. (2011). National safety and efficacy study of PrePex, a new device facilitating non-surgical, bloodless circumcision with no anesthesia and no sutures, for resource-limited settings. American Urology Association Annual Meeting 2011, Session 598. Washington, DC.

Other internally generated reports[edit | edit source]

PrePex. (2011). PrePex overview. Link available here.

Externally generated reports[edit | edit source]

Stein, M. (2011). Circumcision: Rwanda's quick cut to fight HIV. BBC Focus on Africa. Link available here.

Wallace, C. (2011). Rwanda investigating adult male circumcision sans anesthesia. Scientific American. Link available here.

Approval by regulatory bodies or standards boards[edit | edit source]

Certified CE Mark Class IIa and is manufactured using USP Class VI biocompatible elastomeric materials compliant to ISO_13485 Medical Devices (Quality Management systems) and FDA, 21 CFR177. 2600. Circ MedTech is ISO 13485 certified.

FA info icon.svgAngle down icon.svgPage data
Part of Global Health Medical Device Compendium
SDG SDG03 Good health and well-being, SDG09 Industry innovation and infrastructure
Authors Eva Shiu, Amir Sabet
License CC-BY-SA-3.0
Language English (en)
Translations Polish
Related 1 subpages, 5 pages link here
Impact 409 page views
Created January 11, 2012 by Amir Sabet
Modified September 27, 2022 by Irene Delgado
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