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Miraculins Biomarker

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This Global Health Medical Device is designed for or implemented within resource-limited settings - Browse the devices - Add a device

Health Topic Maternal mortality
Classification Diagnosis
Scope Prototype
Location North America

Problem being addressed[edit]

Pre-eclampsia affects over three million mothers worldwide each year and is also associated with premature birth. Regular blood pressure (BP) monitoring is a cost-effective means of identifying hypertensive diseases in their early stages. However, there are currently no effective ways to detect a women’s likelihood to suffer from pre-eclampsia prior to developing the condition.

Detailed description of the solution[edit]

The research done to advance this device is the first major development of a reliable biomarker diagnostic that can accurately predict the onset of pre-eclampsia. The presence of this biomarker also strongly suggests that pre-eclampsia is characterized by abnormal placenta formation which limits the amount of oxygen that can be delivered to the developing fetus during pregnancy. If these biomarkers can detect pre-eclampsia at its earliest stages, there is a high likelihood that maternal and infant death resulting from this condition can be reduced.

Designed by[edit]

  • Designed by: Dr. Isabella Caniggia of the Samuel Lunenfeld Research Institute
  • Manufacturer location: Manitoba, Canada

Funding Source[edit]

Miraculins, Inc.


Other internally generated reports[edit]

Miraculins Inc. (2013, March 11). Miraculins to License Additional Preeclampsia 
Technology from Mount Sinai Hospital. Retrieved from here

Externally generated reports[edit]

Miraculins Inc. (2010, July 13). Miraculins Announces Issuance of Important Preeclampsia Patent in United States. Retrieved from here

(2013). Miraculins Pre-Eclampsia Markers. Mandate. Retrieved from here

IP and copyright[edit]

US Patent 7,754,495 entitled "Methods for Early Diagnosing of an Increased Risk of Preeclampsia"