Problem being addressed[edit | edit source]

There is a lack of an accurate, swift, and low-cost test for the diagnosis of TB. These factors make the disease prevalent in resource-limited settings, leading to the continued spreading of the disease.

Detailed description of the solution[edit | edit source]

Partnering with industry and business, Madhukar Pai and his team seek to develop a simple strip test for extra-pulmonary TB with greater accuracy than current processes. A strip test generally involves the detection of lipoarabinomannan (LAM) in urine. The presence of LAM in urine can rule-in TB in HIV-infected persons, and lead to the identification of, based on clinical trials, patients with advanced immunosuppression and thus a more severe form of TB. They plan to make each test cost less than two dollars.

Designed by[edit | edit source]

  • Designed by: Madhukar Pai and the Pai Tuberculosis Research Group based at McGill Univeristy
  • Manufacturer (if different): n/a
  • Manufacturer location: n/a

Funding Source[edit | edit source]

Received grant from Grand Challenges Canada as of Jun 29, 2011.

References[edit | edit source]

Other internally generated reports[edit | edit source]

  • "A Low-Cost, Multiplexed, Point-of-Care Test for Extra-Pulmonary Tuberculosis."

Retrieved on Jul 17, 2014 from

Video[edit | edit source]

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