|Replicated? Was this project made independently by someone other than the authors and without their guidance?|
|Countries of design|
|Countries of replication|
Problem being addressed[edit | edit source]
There is a need to develop CD4 counters that do not rely on laboratory workers and expensive/complicated equipment. A counter that can be used by rural clinicians in the field without extensive training would greatly assist in managing HIV in rural areas.
Detailed description of the solution[edit | edit source]
Microfluidic cell chromatography isolates cells and other particles in a miniature sensing chamber, without the complex manual steps of blood tests. The system takes advantage of electrochemical sensing, using lysate impedance spectroscopy. The system uses a simple sensor that counts the captured CD4 cells by measuring their internal contents electrically. A hand-held instrument interprets the electrical signal, and reports the CD4 count within minutes.
Designed by[edit | edit source]
- Designed by: Daktari Diagnostics
- Manufacturer location: Cambridge, Massachusetts, USA
When and where it was tested/implemented[edit | edit source]
A clinical trial took place in Seattle the summer of 2010 and clinical trials have also been conducted in Uganda.
Funding Source[edit | edit source]
Funded privately and through the Gates Foundation.
References[edit | edit source]
Externally generated reports[edit | edit source]
McBride R. (2009.) Daktari Diagnostics, backed by Gates Foundation, raises funds for HIV test study. Link available here