Problem being addressed[edit | edit source]

There is a need to develop CD4 counters that do not rely on laboratory workers and expensive/complicated equipment. A counter that can be used by rural clinicians in the field without extensive training would greatly assist in managing HIV in rural areas.

Detailed description of the solution[edit | edit source]

Microfluidic cell chromatography isolates cells and other particles in a miniature sensing chamber, without the complex manual steps of blood tests. The system takes advantage of electrochemical sensing, using lysate impedance spectroscopy. The system uses a simple sensor that counts the captured CD4 cells by measuring their internal contents electrically. A hand-held instrument interprets the electrical signal, and reports the CD4 count within minutes.

Designed by[edit | edit source]

  • Designed by: Daktari Diagnostics
  • Manufacturer location: Cambridge, Massachusetts, USA

When and where it was tested/implemented[edit | edit source]

A clinical trial took place in Seattle the summer of 2010 and clinical trials have also been conducted in Uganda.

Funding Source[edit | edit source]

Funded privately and through the Gates Foundation.

References[edit | edit source]

Externally generated reports[edit | edit source]

McBride R. (2009.) Daktari Diagnostics, backed by Gates Foundation, raises funds for HIV test study. Link available here

Discussion[View | Edit]

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