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Diabetes mellitus cured - George's experience
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=== Diabetes is CURABLE, but. === * Diabetes is indubitably curable. * Cure is not as fast as Prof. Roy Taylor et al of Newcastle University UK claimed in their [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3168743/?tool=pubmed paper] [1]. * The paper was presented at the American Diabetes Association conference on June 24, 2011 and published in Diabetologia (2011) 54:2506-2514. * It has 46 References! (<small>The article is also available online with open access (Distributed under the terms of the relative Commons Attribution Noncommercial License which permits any noncommercial use, distribution and reproduction in any medium, provided the original author(s) and source are credited) at Springerlink.com.</small>) * The fact is that the claim of cure of diabetes made in this [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3168743/?tool=pubmed paper] [1] appears to be only partially true. * It is vividly brought out in the second paragraph of second column of Diabetologia (2011) 54:2511. That paragraph titled ''Post-intervention observation'' says: "At follow-up 12 weeks after completion of the dietary intervention...... HbA<sub>1c</sub> was unchanged (6.0 +/- 0.2 vs 6.2 +/- 0.1% [42 +/- 2 vs 44 +/- 1 mmol/mol]; p=0.10) and fasting plasma glucose increased modestly (5.7 +/- 0.5 vs 6.1 +/- 0.2 mmol/l; p<0.01), with a 2 h OGTT plasma glucose of 10.3 +/- 1.0 mmol/l. Three participants had recurrence of diabetes as judged by a 2 h post-load plasma glucose > 11.1 mmol/l......." Elsewhere in the [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3168743/?tool=pubmed article] [1] one finds values of "Fasting concentration" of Glucose for different cases and on different days during the course of this research. As these are expressed in "mmol/l" unit, an attempt is made to represent those in "mg/dl" which is more popular among laymen and hence easily comprehensible to common men. They are tabulated below. {| class="wikitable" ! Fasting Concentration ! Controls ! Baseline ! Week 1 ! Week 4 ! Week 8 ! Week 8+12 ! 2Hr OGTT at Week 20 |- | Plasma glucose (mmol/l) | 5.3 +/- 0.1 | 9.2 +/- 0.4 | 5.9 +/- 0.4 | 5.7 +/- 0.6 | 5.7 +/- 0.5 | 6.1 +/- 0.2 | 10.3 +/- 1.0 |- | Serum blood glucose (mg/dl) | 95.5 +/- 1.8 | 165.7 +/- 7.2 | 106.3 +/- 7.2 | 102.7 +/- 10.8 | 102.7 +/- 9.01 | 109.9 +/- 3.6 | 185.0 +/- 18.0 |} Comparison of these numbers with their specified limits given in the table below and taking note of the escalation of FBS in spite of "advice on portion size and healthy eating", clearly indicate that the '''cure''' is but a temporary phenomena in the case of this research, as explained in the "[[Diabetes mellitus cured - George's experience#The pit-falls|The pit-falls]]" section here. CURE is far far away, "long way to go before one can sleep". {| class="wikitable" ! Concentration ! Fasting lower limit ! Fasting upper limit ! 2 hr PP ! 2 hr OGTT |- | Plasma glucose (mmol/l) | 3.89 | 5.55 | 7.77 | 7.77 |- | Serum blood glucose (mg/dl) | 70 | 100 | 140 | 140 |} The fact that 3 out of 7 claimed to be "cured" have already been reverted to diabetes in three months (2 h post-load plasma glucose > 11.1 mmol/l) makes the result statistically non-significant - though NOT insignificant (only 4 out of 11 = 36.36 %). This does not mean or imply that diabetes be incurable. It only means that some more time and effort were required. The Newcastle University team did not complete the LAST MILE and hence missed the goal! Probably the ADA conference date persuaded them to prepare and make a declaration prematurely. Look at my results at ([[Diabetes mellitus cured - George's experience#Lab results from July 2006|Lab results from July 2006.]]). Results given above show that all the participants of this experiment are at the fag end of the last lap of their race towards recurrence of diabetes by the end of third month of "normal diet" with advice on portion size & healthy eating.
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