{"id":56893,"key":"Global_Health_Medical_Device_Compendium/Low-Cost_Strip_Test","title":"Global Health Medical Device Compendium/Low-Cost Strip Test","latest":{"id":1267880,"timestamp":"2026-09-10T14:54:21Z"},"content_model":"wikitext","license":{"url":"https://www.appropedia.org/Appropedia:Copyrights","title":"CC-BY-SA-4.0"},"source":"{{GHMDC device data\n| health-topic = Tuberculosis,\n| classification = Diagnosis\n| made = No\n| replicated = No\n| manufacturer-location = Quebec, Canada\n}}\n\nThere is a lack of an accurate, swift, and low-cost test for the diagnosis of TB. These factors make the disease prevalent in resource-limited settings, leading to the continued spreading of the disease.\n\n== Detailed description of the solution ==\n\nPartnering with industry and business, Madhukar Pai and his team seek to develop a simple strip test for extra-pulmonary TB with greater accuracy than current processes. A strip test generally involves the detection of lipoarabinomannan (LAM) in urine. The presence of LAM in urine can rule-in TB in HIV-infected persons, and lead to the identification of, based on clinical trials, patients with advanced immunosuppression and thus a more severe form of TB. They plan to make each test cost less than two dollars.\n\n== Designed by ==\n\n* Designed by: Madhukar Pai and the Pai Tuberculosis Research Group based at McGill Univeristy\n* Manufacturer (if different): n/a\n* Manufacturer location: n/a\n\n== Funding Source ==\n\nReceived grant from Grand Challenges Canada as of Jun 29, 2011.\n\n== References ==\n\n=== Other internally generated reports ===\n\n* \"A Low-Cost, Multiplexed, Point-of-Care Test for Extra-Pulmonary Tuberculosis.\"\n\nRetrieved on Jul 17, 2014 from http://www.grandchallenges.ca/grantee-stars/0026-01/.\n\n* \"Canadian rising stars receive global health awards\" (Jun 29, 2011). Retrieved on Jul 30, 2014 from http://web.archive.org/web/20140930181442/http://muhc.ca/patients/news/canadian-rising-stars-receive-global-health-awards.\n* Peter JG, Theron G, Dheda K. \"Can point-of-care urine LAM strip testing for tuberculosis add value to the clinical decision making in hospitalized HIV-infected persons? (Feb 4, 2013). Retrieved on Jul 19, 2014 from http://www.ncbi.nlm.nih.gov/pubmed/23390504.\n\n=== Video ===\n\n* \"Madhukar Pai.\" Retrieved on Jul 30, 2014 from http://web.archive.org/web/20110919053951/http://www.grandchallenges.ca:80/canadianrisingstars_round1grantees/madhukarpai_en/.\n\n{{Page data\n| sdg = SDG03 Good health and well-being\n| license = CC-BY-SA-3.0\n| language = en\n}}"}