{"id":39040,"key":"Global_Health_Medical_Device_Compendium/Daktari_CD4","title":"Global Health Medical Device Compendium/Daktari CD4","latest":{"id":1267595,"timestamp":"2026-09-10T13:52:35Z"},"content_model":"wikitext","license":{"url":"https://www.appropedia.org/Appropedia:Copyrights","title":"CC-BY-SA-4.0"},"source":"[[File:Daktari.jpg|thumb]]\n\n{{GHMDC device data\n| health-topic = HIV/AIDS\n| classification = Diagnosis\n| scope = Clinical trial\n| made = No\n| replicated = No\n| manufacturer-location = Massachusetts, United States\n}}\n\nThere is a need to develop CD4 counters that do not rely on laboratory workers and expensive/complicated equipment. A counter that can be used by rural clinicians in the field without extensive training would greatly assist in managing HIV in rural areas.\n\n== Detailed description of the solution ==\n\nMicrofluidic cell chromatography isolates cells and other particles in a miniature sensing chamber, without the complex manual steps of blood tests. The system takes advantage of electrochemical sensing, using lysate impedance spectroscopy. The system uses a simple sensor that counts the captured CD4 cells by measuring their internal contents electrically. A hand-held instrument interprets the electrical signal, and reports the CD4 count within minutes.\n\n== Designed by ==\n\n* Designed by: Daktari Diagnostics\n* Manufacturer location: Cambridge, Massachusetts, USA\n\n== When and where it was tested/implemented ==\n\nA clinical trial took place in Seattle the summer of 2010 and clinical trials have also been conducted in Uganda.\n\n== Funding Source ==\n\nFunded privately and through the Gates Foundation.\n\n== References ==\n\n=== Externally generated reports ===\n\nMcBride R. (2009.) Daktari Diagnostics, backed by Gates Foundation, raises funds for HIV test study. Link available [http://www.xconomy.com/boston/2010/06/17/daktari-diagnostics-backed-by-gates-foundation-raises-funds-for-hiv-test-study/ here]\n\n{{Page data\n| sdg = SDG03 Good health and well-being, SDG09 Industry innovation and infrastructure\n| license = CC-BY-SA-3.0\n| language = en\n}}"}