This page is dedicated to open source bioreactors. Commercial OS: https://chi.bio/
Citation List For Papers Use and Design of Bioreactors
- Rezakazemi, M., Maghami, M., & Mohammadi, T. (2017, November 22). High loaded synthetic hazardous wastewater treatment using lab-scale submerged ceramic membrane bioreactor. Periodica Polytechnica Chemical Engineering. Retrieved May 18, 2022, from https://pp.bme.hu/ch/article/view/11459The set up consisted of aerated bio-reactor with working volume of 10 L and a dispensing pump transferring feed from the feed tank to the aerated bioreac-tor. Three ceramic microfilters (ID = 9 mm, OD = 14 mm, Length = 25 cm) were connected to a collector where a plastic tube connected the collector to the permeate tank. The per-meate tank was vacuumed employing a vacuum pump (BCV vacuum pumps, P 2-S). Vacuum pressure was indicated using an analog pressure gauge. A pH meter (Lab-215, palintest Inc.) and a dissolved oxygen (DO) probe (HACH, Germany) were also installed in the SCMBR to monitor pH and DO online. SCMBR operation temperature and steady-state continu-ous flow rate were held at 32 °C and 3 mL/min (resulting in hydraulic retention time (HRT) of 32 h), respectively
- For uniform drying and avoiding mechanical stress when tubes were dried, the wet extrudates were placed inside an oven at 100 °C for a few hours. After that, the dried extrudates were placed inside a furnace (Zohouri Furnace Industries) to be sintered with a heating rate of 2 °C/min at 1225 °C for 3 h. Finally, ceramic tubular membranes of 9 mm ID, 14 mm OD and 25 cm length were obtained.
- Pal, P., & Dey, P. (2012, December 22). Process intensification in lactic acid production by three stage membrane integrated hybrid reactor system. Chemical Engineering and Processing: Process Intensification. Retrieved May 4, 2022, from https://www.sciencedirect.com/science/article/pii/S0255270112002516?casa_token=IaWk2rXD8sMAAAAA%3A3OsAw-TMVcaDxigbGFQ2vvmY1l86p-T6H6gZO0bjHVqLiRFOXSLQepNekYqDrPZT-QbRysvK9A
- There is a detailed diagram of the bioreactor included
- Detailed analyzations of the PH levels needed to complete the procedure are provided
- Lim, S. Y., & Ghazali, N. F. (2020, March 20). Product removal strategy and fouling mechanism for cellulose hydrolysis in enzymatic membrane reactor - waste and biomass valorization. SpringerLink. Retrieved May 6, 2022, from https://link.springer.com/article/10.1007/s12649-020-01020-6
- 10 g/L of microcrystalline cellulose was hydrolyzed with cellulase and the hydrolysis reaction was performed in a 100 ml Scott bottle with 0.05 M citrate buffer at pH 5.0 for 72 h. The hydrolysis reaction was controlled at 50 °C under a magnetic stirrer at 100 rpm. There were two product removal strategies for UF, which were Strategy I and Strategy II. For Strategy I, 50% of hydrolysate was filtered after 4 h of hydrolysis reaction to remove the reducing sugar from the hydrolysis reactor,
- There is detailed specifications of a bioreactor used for cellulose hydrolysis in this literature
- Giwa, A., Dindi, A., & Kujawa, J. (2018, June 12). Membrane bioreactors and electrochemical processes for treatment of wastewaters containing heavy metal ions, organics, micropollutants and dyes: Recent developments. Journal of Hazardous Materials. Retrieved May 18, 2022, from https://www.sciencedirect.com/science/article/pii/S0304389418304655?via%3Dihub
- Electronic materials used in the bioreactor process listed in the literature
- Electrode materials that have been used in recent studies include monopolar and bipolar forms of stainless steel, boron doped diamond, aluminum/copper/magnesium alloy, granular and powdered activated carbon, stainless steel coated with single-walled carbon nanotubes, Al/Fe-impregnated granular activated carbon, air, etc. in parallel/rectangular, cylindrical, rotating impeller, and moving particle configurations.
- Demirkol, G. T., Dizge, N., Acar, T. O., Salmanli, O. M., & Tufekci, N. (2017, July 31). Influence of nanoparticles on filterability of fruit-juice industry wastewater using submerged membrane bioreactor. Water Science and Technology. Retrieved May 18, 2022, from https://iwaponline.com/wst/article/76/3/705/27162/Influence-of-nanoparticles-on-filterability-of
- Details an example of bioreactors in the food industry
- PES membrane was placed on the flat membrane modules and nano-sized ZnO (5 mg/L) solution was passed through the membrane for 24 h at 25 ± 1 °C (30 mL/min flow rate).
- Wang, X., Chang, V. W. C., & Tang, C. Y. (2016, January 6). Osmotic membrane bioreactor (OMBR) technology for wastewater treatment and reclamation: Advances, challenges, and prospects for the future. Journal of Membrane Science. from https://www.sciencedirect.com/science/article/pii/S0376738816300096#f0010
- Contains brief description on bioreactors used in osmosis
- Has multiple tables with characteristics
- In depth diagrams of bioreactors
- Mishra, S., Singh, V., Cheng, L., Hussain, A., & Ormeci, B. (2022, March 5). Nitrogen Removal from wastewater: A comprehensive review of biological nitrogen removal processes, critical operation parameters and Bioreactor Design. Journal of Environmental Chemical Engineering.from https://www.sciencedirect.com/science/article/pii/S2213343722002603
- In depth chemical reaction processes included
- Schematic bioreactor processes
- Multiple tables including in depth bioreactor specifications
- Bioreactor diagrams with processes
- Lepine, C., Christianson, L., Davidson, J., & Summerfelt, S. (2018, September 15). Woodchip bioreactors as treatment for recirculating aquaculture systems' wastewater: A cost assessment of nitrogen removal. Aquacultural Engineering. https://www.sciencedirect.com/science/article/pii/S0144860918300840?pes=vor
- Multiple calculations and equations relating to bioreactor characteristics
- Bioreactor cost analysis, helps display cost
- Several tables displaying bioreactor specifications
- Multiple useful sources referenced and used in this article
- Magar, S. T. (2021, September 14). Bioreactor- definition, design, principle, parts, types, applications, limitations. Microbe Notes, from https://microbenotes.com/bioreactor/
- Full description of bioreactor functions and uses
- Examples of bioreactor sizes to scale and reference
- Multiple examples of different bioreactors listed and displayed
- Dahiya, S., & Mohan, S. V. (2022, April 28). Synergy of selective buffering, intermittent ph control and bioreactor configuration on acidogenic volatile fatty acid production from food waste. Chemosphere. from https://www.sciencedirect.com/science/article/pii/S0045653522012486
- In depth analysis and experimental procedure of food waste conversion into fatty acids using bioreactors
- Specifications of bioreactors and diagrams included
- Detailed PH analysis including calculations and graphs
- Rout, P. R., Dash, R. R., Bhunia, P., Lee, E., & Bae, J. (2021, September 23). Comparison between a single unit bioreactor and an integrated bioreactor for nutrient removal from domestic wastewater. Sustainable Energy Technologies and Assessments. from https://www.sciencedirect.com/science/article/pii/S2213138821006342
- The main focus was comparing types of bioreactors and their specifications, materials and methods were focused on as well
- Testing and experimental analysis was performed comparing efficiency of more than one type of bioreactors
- Detailed bioreactor diagrams included
- Falahti-Marvast, H., & Karimi-Jashni, A. (2015, July 28). Performance of simultaneous organic and nutrient removal in a pilot scale anaerobic–anoxic–oxic membrane bioreactor system treating municipal wastewater with a high nutrient mass ratio. International Biodeterioration & Biodegradation. from https://www.sciencedirect.com/science/article/pii/S096483051530041X?via%3Dihub \
- The main focus is to utilize a bioreactor system to purify water
- Several tables displaying specifications and equations
- Multiple graphs displaying efficiency provided
- Selden, C., & Fuller, B. (2018, April 24). Role of Bioreactor Technology in tissue engineering for clinical use and therapeutic target design. Bioengineering (Basel, Switzerland), from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6027481/
- This article focuses on the use of bioreactors in medicine, it is seen there is several bioreactor types mentioned
- Several important components and mechanical aspects to bioreactors are elaborated on
- A key focus is to involve the bioreactors in tissue engineering
- Narayanan, C. M., & Narayan, V. (2019, December 11). Biological wastewater treatment and Bioreactor Design: A Review - Sustainable Environment Research. BioMed Central, from https://sustainenvironres.biomedcentral.com/articles/10.1186/s42834-019-0036-1
- There is several methods and equations elaborated on in this article for the usage of bioreactors in water sanitation
- Anaerobic digestion, on the other hand, is a much slower process. Also, since methanogenic bacteria are obligatory, they are quite sensitive to the operating temperature and pH of the medium, with pH = 7.0 and T = 330–35 °C being the ideal values.
- Nascu, I., Sebastia-Saez, D., Chen, T., & Du, W. (2021, September 8). A combined computational-fluid-dynamics model and control strategies for perfusion bioreactor systems in tissue engineering. IFAC-PapersOnLine. Retrieved May 18, 2022, from https://www.sciencedirect.com/science/article/pii/S2405896321010351
- Bioreactors are machines that develop biological and/or biochemical processes under strict control and monitoring of operational and environmental variables such as temperature, pH, pressure, waste disposal, and nutrient delivery. They may help with in-vitro tissue formation by supplying biochemical and physical regulatory signals.
- This article focuses on the usage of computational methods involved with a bioreactor for tissue engineering
- Al-Asheh, S., Bagheri, M., & Aidan, A. (2021, June 5). Membrane bioreactor for wastewater treatment: A Review. Case Studies in Chemical and Environmental Engineering. Retrieved May 10, 2022, from https://www.sciencedirect.com/science/article/pii/S2666016421000311
- Focuses on utilizing a membrane bioreactor for wastewater sanitation
- Membrane bioreactors are made by combining the biological process with membrane filtration, which has several advantages over traditional technologies like activated sludge. MBR is commonly used for municipal and industrial wastewater treatment.
- Tables including in depth specifications for this type of bioreactor are included as well as an advantages and disadvantages table
- Connelly, S., Shin, S. G., Dillon, R. J., Ijaz, U. Z., Quince, C., Sloan, W. T., & Collins, G. (1AD, January 1). Bioreactor scalability: Laboratory-scale bioreactor design influences performance, ecology, and community physiology in expanded granular sludge bed bioreactors. Frontiers. Retrieved May 10, 2022, from https://www.frontiersin.org/articles/10.3389/fmicb.2017.00664/full
- The full scale bioreactor utilized in the article has a total working volume of 425 m3 with a geometric diameter-to-height ratio of 7:12. It runs semi-continuously at 37°C with an average OLR of 9 g COD/Lreactor.d (s.d. 2 g COD/Lreactor.d).
- There is in depth specifications on the methods as well as the materials used to create this bioreactor
- Capodici, M., Cosenza, A., Di Trapani, D., Mannina, G., Torregrossa, M., & Viviani, G. (2017, June 9). Treatment of oily wastewater with membrane bioreactor systems. MDPI. Retrieved May 10, 2022, from https://www.mdpi.com/2073-4441/9/6/412/htm
- The membrane module was cleaned physically using the approach indicated. The membrane module was removed from the bioreactor and cleaned as follows: light mechanical cleaning with tap water at 0.4–0.5 bar for 15 minutes; then mechanical agitation in water for 5 minutes; next ultrapure water at 0.2 bar for 5 minutes. Chemical cleaning after physical cleaning was accomplished by submerging the membrane module in a citric acid solution with a pH of 2.5 for 12 hours.
- In depth procedure on the cleaning of the bioreactor was included, this allows for multiple usage of the bioreactor
- Asante-Sackey, D., Rathilal, S., Tetteh, E. K., & Armah, E. K. (2022, February 27). Membrane bioreactors for produced water treatment: A mini-review. MDPI. from https://www.mdpi.com/2077-0375/12/3/275/htm
- Ceramic, polymeric, composite, and modified membranes are the materials utilized to create these membranes. Although ceramic membranes have excellent fouling resistance, chemical and mechanical stability, and low operating costs, polymeric membranes are a popular choice for membrane bioreactors due to their high manufacturing costs and brittle nature.
- There is a focus on the types of materials that could be used to create an efficient bioreactor with minimal costs
- Pervez, M. N., Balakrishnan, M., Hasan, S. W., Choo, K.-H., Zhao, Y., Cai, Y., Zarra, T., Belgiorno, V., & Naddeo, V. (2020, November 5). A critical review on nanomaterials membrane bioreactor (NMS-MBR) for wastewater treatment. Nature News. Retrieved May 8, 2022, from https://www.nature.com/articles/s41545-020-00090-2
- Submerged (SMBRs) and side stream MBRs are the two basic classifications of MBRs, depending on their design and hydrodynamic control of membrane fouling. This technique, which was first presented more than 30 years ago, has the following benefits: a smaller footprint, high-quality treated water, reduced sludge generation, low energy consumption, and a greater pollutant removal rate. MBRs are thus preferred over other techniques for obtaining high-quality treated wastewater, such as activated carbon adsorption, filtration, coagulation, and so on; they can also be combined with oxidation processes such as photolysis, sonolysis, and chemical/electrochemical oxidation for the removal of micropollutants.
- The comparison between two widely used bioreactors is included displaying a efficient option for building a bioreactor
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- Wong, B.G., Mancuso, C.P., Kiriakov, S., Bashor, C.J. and Khalil, A.S., 2018. Precise, automated control of conditions for high-throughput growth of yeast and bacteria with eVOLVER. Nature biotechnology, 36(7), pp.614-623. (https://www.nature.com/articles/nbt.4151). (https://www.fynchbio.com/documentation).
- Marinescu, G.C. and Popescu, R.G., 2018. Open-Source bioreactor controller for bacterial protein expression. PeerJ Preprints, 6, p.e27150v1.https://peerj.com/preprints/27150.pdf
- Jenny Malloy's https://openbioeconomy.org/projects/open-source-bioreactor/,
- https://github.com/Biomaker/2018-opensourcebioreactor
- https://create.arduino.cc/projecthub/open-bioeconomy-lab/microbial-bioreactor-d7f61b
- https://www.hackster.io/open-bioeconomy-lab/microbial-bioreactor-d7f61b
