Multichannel Pipette Literature Review

Hans Jirgen Bigus Uhl, “MULTI-CHANNEL PIPETTE DEVICE” Patent Application Publication

  • each pipette channel has at least one associated, separate micro membrane pump for dosed Suction and/or discharge of fluids
  • informative for the basic structure
  • tells us about the internal working

Kenneth Rainin, Walter S. Watson "LIQUID-END ASSEMBLY FOR MULTICHANNEL AIR-DISPLACEMENT PIPETTE" United States Patent

  • Give a detailed insight into the working of a multichannel pipette containing a single cylinder for each individual channel.
  • Discusses the advantages of being able to replace a single cylinder at a time, depending on the requirement.
  • Elaborates on the mechanism used to eject spent tips without touching them.

Khastsaev, B.D. Single channel and multichannel adjustable micropipettes. Biomed Eng 27, 285–291 (1993).

  • Gives a detailed description of the classification of pipettes depending upon their types, volumes, number of channels, and on other parameters.
  • Details both domestic and foreign pipette manufacturers while also stating some advantages and disadvantages of some of their products.

Kenneth O'Connell and Nicholas Vitale "LIQUID END ASSEMBLY FOR A HANDHELD MULTICHANNEL PIPETTE WITH ADJUSTABLE NOZZLE SPACING" United States Patent

  • Design for 8 nozzle pipette with the varying distance between adjacent tips is achieved using the inline alignment technique which is controlled by using the knob like fasteners
  • working mechanism is explained here with the minute part details

Martin Klingenberg, “When a common problem meets an ingenious mind” The invention of the modern micropipette"EMBO Reports"

  • invention of the piston-driven, plastic-tip micropipette
  • breakthrough in the invention of the micropipette
  • introduction of coaxial springs
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