Motivation

Current situation

  • World Health Organisation's index page on Ebola
  • From WHO's fact sheet:
    • Ebola virus disease (EVD), formerly known as Ebola haemorrhagic fever, is a severe, often fatal illness in humans.
    • The virus is transmitted to people from wild animals and spreads in the human population through human-to-human transmission.
    • The average EVD case fatality rate is around 50%. Case fatality rates have varied from 25% to 90% in past outbreaks. (Note: current west Africa epidemic is on-going, so fatality rates are not easy to compute. Modelers have computed figures around 70%.)
    • The first EVD outbreaks occurred in remote villages in Central Africa, near tropical rainforests, but the most recent outbreak in west Africa has involved major urban as well as rural areas.
  • WHO's situation reports. (We'll update it every now and then, specially if it changes the "what to do" picture.) 7470 (probable, confirmed and suspected) cases and 3431 deaths have been reported in the current outbreak of EVD up to the end of 1 October 2014 by the Ministries of Health of Guinea, and Sierra Leone, and up to the end of 30 September by the Ministry of Health of Liberia. Three countries have now reported a case or cases imported from a country with widespread and intense transmission: Nigeria (20 cases and 8 deaths), Senegal (1 case, no deaths), United States of America (1 case, 30 September 2014).
  • (Link needed.) Some experts suggest real figures could be official figures multiplied by 2.5, because many cases are reported late or are not reported at all.

Possible futures

  • (Link needed.) Modelers suggest the number of cases is doubling every 2-3 weeks. At this pace, figures of up to one million cases or more for the end of 2014 have been mentioned. This would be the upper boundary of the current trend, if unstopped.
  • (Links needed.) Other "worse cases" have been suggested: extension of the epidemic within Africa (Mali, etc) or to other continents (Asia), the disease becoming endemic in the human population (not needing further re-seeding from fruit bats or other animals into human populations), the virus becoming more efficient at the current mode of transmission, or even the virus becoming capable of other transmission routes.
  • The best way to avoid all those possible futures is to stop the current outbreak, and that's where most efforts should go. A small percentage of the efforts are needed to do surveillance and know things have changed (if and when they have), and to plan for such dire scenarios.

Open-source appropriate technology

  • WHO and AT for Ebola: Due to the urgency of the Ebola outbreak and the WHO’s scale up of international response in west Africa, WHO is providing technical information on appropriate available essential medical devices which are indispensable for treatment centres, community-based units and other preventive activities, in affected and neighbouring countries.
  • 2014 call for innovative technologies WHO is searching for innovative health technologies that can be used for infection prevention and control (IPC), diagnosis, and supportive care. 2014 call for innovative technologies.
  • USAID Fighting Ebola: A Grand Challenge for Development.

What we could do

Beware, reader

Ebola is life and death for many people. This page is bits on the internet. Double-check every fact, validate externally, and add lots of common sense and cautionary principle.

A generative process

Pharmaceutical companies start developing many products, and only some of them become commercial products. Likewise, many ideas will prove to be useless or worse. So maybe there's need for some light, open, perfectible process. The following steps are suggested:

  • Ask what's needed. Look at (anonymised or at least respectful) videos of caregivers giving care, people burying the dead, etc. Comb news and conversations for facts: what do people do, who to, how often? Just as a made-up example: cleaning vomit, an average of 10 times a day for an average of 7 days. Adding all that up would give us an approximation of the per-patient workload.
  • Look at obvious and not so obvious ideas. Look at what doesn't work and reverse some features (this is how the "excubator" concept came about). Look at resources on the ground. Develop other people's ideas. Challenge your own thinking: what is it that you assume, and could you take a different route?
  • Develop and document prototypes. Build it, do some role-playing, shoot (anonymised or at least respectful) video. Share with experts in science, care, building. Improve the prototype. Rinse and repeat.
  • Ask for external validation. Somebody may eventually do careful small tests. But before that, what do experts in science, care, and building think of your best efforts?

Even this process can be improved. Please do.

Areas in need of useful ideas

If Ebola is duplicating every 2-3 weeks, then containment would work if we reduce current contagions by 50% or more. There's need to care for the sick. There's also need to keep all the other essential activities of societies running: keep caregivers fed, take care of the orphans and PSTD'ed. It is suggested that all other activities are secondary to these main ones: funding, helping hands, education, etc - all are means to the end of reducing contagions, caring for the ill and keeping vital stuff working.

One useful framework might be SCIM, which has been adapted for severe pandemic flu. CDC has done extensive work on community response to influenza pandemics. None of this has been tested for our current concern, so the "beware, reader" comment above applies in full force!

Some examples

  • Tippy tap, an inexpensive and simple to build device for safe hand-washing, has apparently already been used in Ebola care centers, as shown on this article's heading's picture.
  • The notion of an "excubator" (inverse incubator) is being explored. It would be a tall box with a plastic window and gloves coming out. Internal handles and maybe wheels make it easy to port the device from bedside to bedside. A marsupial bag, fed from within through a one-way slot, could be added. An external slide might help with supplies not in the bag, that would be dropped from behind by an assistant. The box would be made of cardboard (can be burned later) or plastic (can be spraywashed).
  • The excubator has been morphed into "bedside wall" and "michelin suit" (oversized suit with foam bricks so that air passes through and the suit is more tolerable).

What else?

(... still thinking ...)

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