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==Problem being addressed==
==Problem being addressed==
There is a need to develop CD4 counters that do not rely on laboratory workers and expensive/complicated equipment. A counter that can be used by rural clinicians in the field without extensive training would go a long way towards managing HIV in rural areas.
There is a need to develop CD4 counters that do not rely on laboratory workers and expensive/complicated equipment. A counter that can be used by rural clinicians in the field without extensive training would greatly assist in managing HIV in rural areas.


==Detailed description of the solution==
==Detailed description of the solution==

Revision as of 13:54, 14 March 2012

FA info icon.svg Angle down icon.svg Medical equipment data

Problem being addressed

There is a need to develop CD4 counters that do not rely on laboratory workers and expensive/complicated equipment. A counter that can be used by rural clinicians in the field without extensive training would greatly assist in managing HIV in rural areas.

Detailed description of the solution

Microfluidic cell chromatography isolates cells and other particles in a miniature sensing chamber, without the complex manual steps of blood tests. This technology addresses the issue that clinicians face when working beyond the reach of sophisticated labs. The second innovation is electrochemical sensing, using lysate impedance spectroscopy. The system uses a simple sensor that counts the captured CD4 cells by measuring their internal contents electrically. A hand-held instrument interprets the electrical signal, and reports the CD4 count within minutes.

Designed by

  • Designed by: Daktari Diagnostics
  • Manufacturer location: Cambridge, Massachusetts, USA

When and where it was tested/implemented

A clinical trial took place in Seattle the summer of 2010 and clinical trials have also been conducted in Uganda.

Funding Source

Private funding. Also, the Bill and Melinda Gates Foundation funded clinical trials.

References

Externally generated reports

McBride R. (2009.) Daktari Diagnostics, backed by Gates Foundation, raises funds for HIV test study. Link available here

McBride R. (2009.) Daktari Diagnostics, backed by Gates Foundation, raises funds for HIV test study. Link available here.

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